Perrot H, Durand L, Thivolet J, Millon M, Ortonne J P
Ann Dermatol Venereol. 1977 May;104(5):381-6.
A 37 years old woman presented with scleroderma en coup de sabre of the head with chronic homolateral ocular hypertony. Skin disorders appeared in the childhood and extended slowly until the age of 20. Glaucoma, found 5 years earlier, was unimproved by medical treatment; the opposite eye was normal. Two goniotomia in 1974 were uneffective. A trabeculectomy in 1975 was followed by scleral fistula with important ocular hypotonia. A scleral flap was followed by the disappearance of hypotonia with no return to previous hypertony. The connections between scleroderma and glaucoma are discussed; vascular and neurologic mechanisms are suggested. Up to now, glaucoma has been reported in patients with systemic soleroderma and Romberg disease.
一名37岁女性，头部患有剑伤性硬皮病，伴有慢性同侧眼压升高。皮肤疾病始于童年，缓慢发展至20岁。5年前发现的青光眼，经药物治疗未改善；对侧眼正常。1974年进行的两次前房角切开术均无效。1975年行小梁切除术后出现巩膜瘘，眼压明显降低。巩膜瓣植入后眼压降低消失，未恢复至之前的眼压升高状态。文中讨论了硬皮病与青光眼之间的联系，并提出了血管和神经机制。迄今为止，已有系统性硬皮病和Romberg病患者发生青光眼的报道。
