细菌对氨基糖苷类抗生素的耐药性。
Bacterial resistance to aminoglycoside antibiotics.
作者信息
Davies J, Wright G D
机构信息
Dept of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
出版信息
Trends Microbiol. 1997 Jun;5(6):234-40. doi: 10.1016/S0966-842X(97)01033-0.
PMID:9211644
Abstract
The aminoglycoside antibiotics are broad-spectrum antibacterial compounds that are used extensively for the treatment of many bacterial infections. In view of the current concerns over the global rise in antibiotic-resistant microorganisms, there has been renewed interest in the mechanisms of resistance to the aminoglycosides, including the superfamily of aminoglycoside-modifying enzymes.
摘要
氨基糖苷类抗生素是一类广谱抗菌化合物，广泛用于治疗多种细菌感染。鉴于当前对全球抗生素耐药微生物增加的担忧，人们对氨基糖苷类抗生素的耐药机制重新产生了兴趣，包括氨基糖苷类修饰酶超家族。
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