Sharma S K, Philip J, Wiley J
University of Texas Southwestern Medical School, Department of Anesthesiology and Pain Management, Dallas 75235-9068, USA.
Anesth Analg. 1997 Jul;85(1):94-8. doi: 10.1097/00000539-199707000-00017.
Thromboelastography (TEG) using disposable plastic cups and pins was performed with native whole blood (native group) in 17 nonpregnant volunteers, 134 healthy term pregnant women (>36 wk gestation), and 69 postpartum women. Thromboelastography was also performed with celite-activated whole blood (celite group) in 15 nonpregnant female volunteers, 38 healthy term pregnant women, and 34 postpartum women. The thromboelastographic parameters r and K were significantly decreased in pregnant and postpartum women compared with nonpregnant women in both groups (P < 0.05). The maximum amplitude MA, elastic shear modulus, and alpha angles were significantly increased in pregnant and postpartum women compared with nonpregnant women in both groups (P < 0.05). The TEG coagulation index was significantly greater in pregnant and postpartum women compared with nonpregnant women in both groups. In this study, TEG showed that pregnancy is a hypercoagulable state and that postpartum women remain hypercoagulable through the first 24 h postdelivery. The use of celite in TEG accelerated the speed of TEG analysis.
使用一次性塑料杯和针进行血栓弹力图（TEG）检测，对17名非妊娠志愿者、134名健康足月孕妇（妊娠>36周）和69名产后女性采集的全血（天然组）进行检测。同时，对15名非妊娠女性志愿者、38名健康足月孕妇和34名产后女性采集的硅藻土激活全血（硅藻土组）也进行了血栓弹力图检测。与两组非妊娠女性相比，妊娠和产后女性的血栓弹力图参数r和K显著降低（P<0.05）。与两组非妊娠女性相比，妊娠和产后女性的最大振幅MA、弹性剪切模量和α角显著增加（P<0.05）。两组中，妊娠和产后女性的TEG凝血指数显著高于非妊娠女性。在本研究中，TEG显示妊娠是一种高凝状态，产后女性在分娩后的前24小时内仍处于高凝状态。在TEG中使用硅藻土加快了TEG分析的速度。
