Bapat P P, Verghese C
Laryngeal Mask Research Centre, Department of Anesthesia, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom.
Anesth Analg. 1997 Jul;85(1):139-43. doi: 10.1097/00000539-199707000-00025.
We studied the incidence of regurgitation in 100 patients undergoing elective gynecological laparoscopies under general anesthesia with intermittent positive pressure ventilation using a laryngeal mask airway (LMA). Patients ingested methylene blue capsules 10-15 min before induction of anesthesia. After induction and insertion of an LMA using the recommended insertion technique, a fiberoptic examination of the larynx was made for traces of dye and to site a pH probe in the bowl of the LMA for continuous monitoring. LMA insertion was successful in all patients within two attempts (95 at first attempt). Fiberoptic examination revealed the vocal cords or cords and posterior or anterior epiglottis in 96 and no trace of dye in 99 patients. One patient regurgitated dye immediately after induction, and the stain was seen on the LMA after removal. The remaining 99 LMAs were not stained. Thirty patients were randomly selected for fiberoptic examination of the laryngopharynx before neuromuscular block was antagonized. Methylene blue staining did not occur in any of these patients. In 91 patients with complete pH data, regurgitation (pH < 4.0) did not occur. The 95% confidence limit for a true probability of regurgitation in this study is 0.041 or a true rate of regurgitation of less than 4.1%. A larger study would be required to possibly demonstrate a lower incidence of regurgitation. This study confirms the clinical impression that the incidence of regurgitation during laparoscopies with a LMA is extremely low.
我们研究了100例择期接受全身麻醉、采用喉罩气道(LMA)并间歇正压通气的妇科腹腔镜手术患者的反流发生率。患者在麻醉诱导前10 - 15分钟吞服亚甲蓝胶囊。在诱导麻醉并使用推荐的插入技术插入LMA后,进行喉镜纤维光学检查以寻找染料痕迹,并在LMA罩碗内放置pH探头进行连续监测。所有患者均在两次尝试内成功插入LMA(95例首次尝试成功)。纤维光学检查显示,96例患者可见声带或声带及会厌前后部,99例患者未见染料痕迹。1例患者在诱导后立即发生染料反流,移除LMA后可见污渍。其余99个LMA未被染色。在拮抗神经肌肉阻滞前,随机选择30例患者进行喉咽纤维光学检查。这些患者均未出现亚甲蓝染色。在91例有完整pH数据的患者中,未发生反流(pH < 4.0)。本研究中反流真实概率的95%置信区间为0.041,即真实反流率低于4.1%。可能需要更大规模的研究来证明更低的反流发生率。本研究证实了临床印象,即使用LMA进行腹腔镜手术期间反流的发生率极低。