Houston A B, Brodie M J, Moore M R, Thompson G G, Stephenson J B
Arch Dis Child. 1977 Aug;52(8):646-50. doi: 10.1136/adc.52.8.646.
A 9-year-old boy with mental deterioration and epilepsy suffered an acute attack of hereditary coproporphyria associated with worsening of seizure control. Leucocyte coproporphyrinogen oxidase activity was undetectable in the patient during this attack, and was reduced in his mother, a latent case. The complex relationship between porphyria, epilepsy, and anticonvulsant drugs is discussed.
一名患有智力衰退和癫痫的9岁男孩遗传性粪卟啉病急性发作，同时癫痫控制情况恶化。在此次发作期间，患者白细胞中的粪卟啉原氧化酶活性检测不到，而其母亲（一名潜伏病例）的该酶活性降低。本文讨论了卟啉病、癫痫和抗惊厥药物之间的复杂关系。
