Takahashi T, Munakata M, Homma Y, Kawakami Y
First Department of Medicine, School of Medicine, Hokkaido University, Sapporo.
Intern Med. 1997 Jun;36(6):435-8. doi: 10.2169/internalmedicine.36.435.
A 46-year-old Japanese woman has been followed up for 3 years due to interstitial pneumonia associated with progressive systemic sclerosis (PSS). During this follow-up period, chest roentgenogram revealed additional diffuse nodular shadows. She was diagnosed as having pulmonary sarcoidosis, which was confirmed by the presence of epitheloid granulomas within the alveolar septa. She was successfully treated with corticosteroids and recovered almost completely without worsening pulmonary abnormalities caused by her PSS. The independent clinical courses of these two diseases in the present case suggest that the complication of PSS and sarcoidosis in this patient may be coincidental.
一名46岁的日本女性因与进行性系统性硬化症（PSS）相关的间质性肺炎接受了3年的随访。在这段随访期间，胸部X线片显示出现了额外的弥漫性结节状阴影。她被诊断为患有肺结节病，肺泡间隔内存在上皮样肉芽肿证实了这一诊断。她接受了皮质类固醇治疗并成功康复，几乎完全恢复，且未出现因PSS导致的肺部异常恶化。本病例中这两种疾病独立的临床病程表明，该患者PSS和结节病的并发可能是巧合。
