The fate of ingested Brugia pahangi microfilariae in susceptible and refractory strains of Culex pipiens and Aedes aegypti.

The uptake and migration of microfilariae of Brugia pahangi in susceptible and refractory Culex pipiens and Aedes aegypti were compared after membrane-feeding the mosquitoes on infected blood and anti-coagulant. There was no difference between the strains within each species in the pattern of migration, but in C pipiens only 24% of the microfilariae reached the thorax whereas in A. aegypti 73-6% were successful. In both susceptible strains the filariae in the thorax developed normally to maturity, but in both refractory strains almost all filariae died within a few days.