鹅肌肽醌A和B：来自粪生真菌嗜粪足孢霉的新型抗真菌和抗菌苯醌类化合物。
Anserinones A and B: new antifungal and antibacterial benzoquinones from the coprophilous fungus Podospora anserina.
作者信息
Wang H, Gloer K B, Gloer J B, Scott J A, Malloch D
机构信息
Department of Chemistry, University of Iowa, Iowa City 52242, USA.
出版信息
J Nat Prod. 1997 Jun;60(6):629-31. doi: 10.1021/np970071k.
PMID:9214737
Abstract
Two new benzoquinones with antifungal, antibacterial, and cytotoxic activities have been isolated from liquid cultures of the coprophilous fungus Podospora anserina. The structures of anserinones A (1) and B (2) were assigned on the basis of MS and NMR results, and the absolute stereochemistry of 2 was deduced by analysis of 1H-NMR data for its (R)- and (S)-2-phenylbutyryl ester derivatives.
摘要
从粪生真菌柄孢壳菌的液体培养物中分离出了两种具有抗真菌、抗菌和细胞毒性活性的新苯醌。根据质谱和核磁共振结果确定了柄孢壳菌素A（1）和B（2）的结构，并通过分析其（R）-和（S）-2-苯基丁酰酯衍生物的1H-核磁共振数据推断出2的绝对立体化学。
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