球形容积内热声层析成像的时域重建

Time-domain reconstruction for thermoacoustic tomography in a spherical geometry.

作者信息

Xu Minghua, Wang Lihong V

机构信息

Department of Biomedical Engineering, Texas A&M University, College Station 77843-3120, USA.

出版信息

IEEE Trans Med Imaging. 2002 Jul;21(7):814-22. doi: 10.1109/TMI.2002.801176.

DOI:10.1109/TMI.2002.801176

PMID:12374318

Abstract

Reconstruction-based microwave-induced thermoacoustic tomography in a spherical configuration is presented. Thermoacoustic waves from biological tissue samples excited by microwave pulses are measured by a wide-band unfocused ultrasonic transducer, which is set on a spherical surface enclosing the sample. Sufficient data are acquired from different directions to reconstruct the microwave absorption distribution. An exact reconstruction solution is derived and approximated to a modified backprojection algorithm. Experiments demonstrate that the reconstructed images agree well with the original samples. The spatial resolution of the system reaches 0.5 mm.

摘要

本文提出了基于重建的球形配置微波诱导热声层析成像方法。由微波脉冲激发的生物组织样本产生的热声波由宽带非聚焦超声换能器进行测量，该换能器设置在包围样本的球面上。从不同方向采集足够的数据以重建微波吸收分布。推导了精确的重建解并近似为改进的反投影算法。实验表明，重建图像与原始样本吻合良好。该系统的空间分辨率达到0.5毫米。