使用七通道梯度计对正常人类受试者进行MEG听觉诱发电场源定位的可重复性。

Reproducibility of MEG auditory evoked field source localizations in normal human subjects using a seven-channel gradiometer.

作者信息

Teale P, Goldstein L, Reite M, Sheeder J, Richardson D, Edrich J, Zimmerman J E

机构信息

Department of Psychiatry, University of Colorado Health Sciences Center, Denver 80262, USA.

出版信息

IEEE Trans Biomed Eng. 1996 Sep;43(9):967-9. doi: 10.1109/10.532131.

DOI:10.1109/10.532131

PMID:9214812

Abstract

Magnetoencephalographic (MEG) auditory evoked fields (EF) were recorded from 12 normal adult subjects over both hemispheres on two separate occasions at least one week apart using a seven-channel second-order gradiometer. Stimuli were computer-generated at 25-msec duration, 1 kHz tone pips. Responses to 100 stimuli were averaged, and source estimates with confidence intervals were computed, for the 100-msec latency auditory EF component, termed M100. Root-mean-squared (rms) differences in x, y, and z locations were approximately 0.7 cm on the two occasions; strength and orientation differences were 18 nA-m and 11 degrees, respectively. This spatial accuracy using a seven-channel instrument, compares favorably with other currently available technologies for localization of brain function.

摘要

使用七通道二阶梯度仪，在至少相隔一周的两个不同时间，从12名正常成年受试者的两个半球记录脑磁图（MEG）听觉诱发电场（EF）。刺激由计算机生成，持续时间为25毫秒，为1千赫的短纯音。对100次刺激的反应进行平均，并计算出100毫秒潜伏期听觉EF成分（称为M100）的带置信区间的源估计值。两次测量中x、y和z位置的均方根（rms）差异约为0.7厘米；强度和方向差异分别为18纳安-米和11度。使用七通道仪器的这种空间精度，与目前其他用于脑功能定位的可用技术相比具有优势。