Howe L M
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4474, USA.
J Am Vet Med Assoc. 1997 Jul 1;211(1):57-62.
To determine short-term results and complications of prepubertal gonadectomy in cats and dogs.
Prospective randomized study.
775 cats and 1,213 dogs.
Animals undergoing gonadectomy were allotted into 3 groups on the basis of estimated age (group 1, < 12 weeks old; group 2, 12 to 23 weeks old; group 3, > or = 24 weeks old). Complications during anesthesia, surgery, and the immediate postoperative period (7 days) were recorded. Complications were classified as major (required treatment and resulted in an increase in morbidity or mortality) or minor (required little or no treatment and caused a minimal increase in morbidity). An ANOVA was used to detect differences among groups in age, weight, body temperature, and duration of surgery. To detect differences in complication rates among groups, chi 2 analysis was used.
Group 1 consisted of 723 animals, group 2 consisted of 532, and group 3 consisted of 733. Group-3 animals had a significantly higher overall complication rate (10.8%) than group-1 animals (6.5%), but did not differ from group-2 animals (8.8%). Differences were not detected among the 3 groups regarding major complications (2.9, 3.2, and 3.0% for groups 1, 2, and 3, respectively), but group-3 animals had significantly more minor complications (7.8%) than group-1 animals (3.6%), but not group-2 animals (5.6%).
In this study, prepubertal gonadectomy did not increase morbidity or mortality on a short-term basis, compared with gonadectomy performed on animals at the traditional age. These procedures may be performed safely in prepubertal animals, provided that appropriate attention is given to anesthetic and surgical techniques.
确定猫和狗青春期前性腺切除术的短期结果及并发症。
前瞻性随机研究。
775只猫和1213只狗。
接受性腺切除术的动物根据估计年龄分为3组(第1组,小于12周龄;第2组,12至23周龄;第3组,大于或等于24周龄)。记录麻醉、手术及术后即刻(7天)的并发症。并发症分为严重(需要治疗且导致发病率或死亡率增加)或轻微(几乎不需要治疗或无需治疗且导致发病率轻微增加)。采用方差分析检测各组在年龄、体重、体温及手术持续时间方面的差异。采用卡方分析检测各组并发症发生率的差异。
第1组有723只动物,第2组有532只,第3组有733只。第3组动物的总体并发症发生率(10.8%)显著高于第1组动物(6.5%),但与第2组动物(8.8%)无差异。3组在严重并发症方面未检测到差异(第1、2、3组分别为2.9%、3.2%和3.0%),但第3组动物的轻微并发症(7.8%)显著多于第1组动物(3.6%)(但与第2组动物(5.6%)无差异)。
在本研究中,与传统年龄动物进行的性腺切除术相比,青春期前性腺切除术在短期内不会增加发病率或死亡率。只要对麻醉和手术技术给予适当关注,这些手术可在青春期前动物中安全进行。