• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在内淋巴中注射氯化钾溶液后耳蜗电位疲劳增加。

Increased fatigue of cochlear potentials after injection of KCl solution in the perilymph.

作者信息

Legouix J P, Pierson A

出版信息

Audiology. 1977 Nov-Dec;16(6):453-61. doi: 10.3109/00206097709080016.

DOI:10.3109/00206097709080016
PMID:921603
Abstract

Cochlear microphonics (CM), action potentials (AP) and endochochlear potential (EP) were recorded on guinea pigs. The introduction of a small quantity of KCl solution (0.1 N) in the perilymph provoked a moderate decrease of CM and AP. During the period of depressed but stable amplitude, the presentation of intense sounds provoked an exaggerated susceptibility to fatigue and a delayed recovery. Similar changes were observed in the evolution of EP. However, the recovery was slower for EP than for CM. The results, as a whole, suggest that the fatigue which is manifested in the depression of cochlear potentials is related to a leakage of potassium ions from endolymph to fluids spaces within the organ of Corti.

摘要

在豚鼠身上记录了耳蜗微音器电位(CM)、动作电位(AP)和内耳蜗电位(EP)。在外淋巴中引入少量氯化钾溶液(0.1N)会引起CM和AP适度下降。在振幅降低但稳定的时期,高强度声音的呈现会引发对疲劳的过度易感性和恢复延迟。在EP的变化过程中也观察到了类似的变化。然而,EP的恢复比CM慢。总体而言,这些结果表明,耳蜗电位降低所表现出的疲劳与钾离子从内淋巴泄漏到柯蒂氏器内的液隙有关。

相似文献

1
Increased fatigue of cochlear potentials after injection of KCl solution in the perilymph.在内淋巴中注射氯化钾溶液后耳蜗电位疲劳增加。
Audiology. 1977 Nov-Dec;16(6):453-61. doi: 10.3109/00206097709080016.
2
Effect of intracochlear aminooxyacetic acid on cochlear potentials and endolymph composition.
Ann Otol Rhinol Laryngol. 1975 Mar-Apr;84(2 PART 1):192-7. doi: 10.1177/000348947508400209.
3
Effects of kanamycin sulfate on cochlear potentials and potassium ion permeability through the cochlear partitions.硫酸卡那霉素对耳蜗电位及钾离子通过耳蜗隔板通透性的影响。
ORL J Otorhinolaryngol Relat Spec. 1987;49(1):9-16. doi: 10.1159/000275900.
4
Ototoxicity of cis-dichlorodiammine platinum (II) in guinea pigs.顺二氯二氨铂(II)对豚鼠的耳毒性。
Am J Otolaryngol. 1983 Jan-Feb;4(1):18-26. doi: 10.1016/s0196-0709(83)80003-9.
5
Effects of exposure to noise on permeability to potassium of the endolymph-perilymph barrier in guinea pigs.噪声暴露对豚鼠内淋巴-外淋巴屏障钾离子通透性的影响。
Acta Otolaryngol. 1982 Nov-Dec;94(5-6):395-401. doi: 10.3109/00016488209128927.
6
Functional importance of sodium and potassium in the guinea pig cochlea studied with amiloride and tetraethylammonium.
Jpn J Physiol. 1982;32(2):219-30. doi: 10.2170/jjphysiol.32.219.
7
Endocochlear potential and potassium concentration in endolymph and perilymph of the chinchilla.豚鼠内淋巴和外淋巴中的耳蜗内电位及钾离子浓度
Arch Otorhinolaryngol. 1980;229(2):149-53. doi: 10.1007/BF00454238.
8
Permeability to chloride ions of the cochlear partition in normal guinea pigs.正常豚鼠耳蜗隔对氯离子的通透性
Hear Res. 1985 Mar;17(3):227-36. doi: 10.1016/0378-5955(85)90067-x.
9
Ion transport in the cochlea of guinea pig. II. Chloride transport.豚鼠耳蜗中的离子转运。II. 氯离子转运。
Acta Otolaryngol. 1978 Sep-Oct;86(3-4):176-84. doi: 10.3109/00016487809124734.
10
Some observations on negative endocochlear potential during anoxia.
Acta Otolaryngol. 1979 May-Jun;87(5-6):506-16. doi: 10.3109/00016487909126459.