Murray R D, Jacey M J
Aviat Space Environ Med. 1977 Nov;48(11):1012-7.
Two subjects each were exposed to pressure equivalents of 50 (SHAD I) and 60 (SHAD II) feet of sea water gauge (FSWG) for 30 and 28 d, respectively. Red blood cell (RBC) count, hemoglobin (Hb) content, and reticulocyte count of venous blood from divers were measured before, during, and after these exposures. RBC count of the divers decreased a maximum of 7.1% in the 50-ft dive and 10.7% in the 60-ft dive compared to surface control values. Hb content fell 7.7% and 11.1% in the 50- and 60-ft dives, respectively, when compared to nondiving subjects. Reticulocyte counts tended to increase late in the pressurization phase and during the recovery. The total month-long responses of Hgb in SHAD I, and RBC, Hgb, and reticulocyte count in SHAD II were significantly altered when compared to those of the surface control subjects. The changes in these factors were directly attributable to the month-long exposure to the total hyperbaric environment. The threshold for hematological effects of chronic exposure to compressed air would seem to lie between 50 and 60 FSWG.
两名受试者分别暴露于相当于50英尺(SHAD I)和60英尺(SHAD II)海水表压(FSWG)的压力下,时长分别为30天和28天。在这些暴露之前、期间和之后,测量潜水员静脉血的红细胞(RBC)计数、血红蛋白(Hb)含量和网织红细胞计数。与水面对照值相比,潜水员的RBC计数在50英尺潜水时最多下降7.1%,在60英尺潜水时下降10.7%。与非潜水受试者相比,Hb含量在50英尺和60英尺潜水中分别下降7.7%和11.1%。网织红细胞计数在增压后期和恢复期间往往会增加。与水面对照受试者相比,SHAD I中Hb的整个为期一个月的反应,以及SHAD II中RBC、Hb和网织红细胞计数的反应均有显著改变。这些因素的变化直接归因于为期一个月的整个高压环境暴露。长期暴露于压缩空气的血液学效应阈值似乎介于50和60 FSWG之间。