Satoh H, Ishikawa H, Yamashita Y T, Naito T, Takahashi H, Kamma H, Saito Y, Ohtsuka M, Hasegawa S
Department of Respiratory Medicine, University of Tsukuba, Japan.
Anticancer Res. 1997 May-Jun;17(3C):2293-6.
Lung cancers in the early stages are frequently detected via mass screening in Japan. The aim of this study is to evaluate the outcome of patients with lung cancer detected via mass screening and to compare them to those in whom the malignancy was detected by symptoms. A total of 774 untreated patients with lung cancer who were admitted to Department of Respiratory Medicine, Tsukuba University Hospital over a 20 year period up to 1995, were analyzed with reference to their reasons for detection of the cancer. In the mass screened group(116 patients), 50.0% of lung cancer was detected at stage I of TNM classification, while only 8.2% of patients with symptoms(561 patients) had stage I lung cancer (p = 0.0001). As lung cancers detected via mass screening were more often at operable stage (stage I, II or IIIA) (p = 0.0001), surgical treatment was chosen more frequently in the mass screened group(p = 0.0001). The outcome of patients with lung cancer detected via mass screening was more favorable than that of the patients detected by their symptoms (p = 0.0002). The early detection of lung cancer via mass screening contributes to improvement of the outcome.
在日本，早期肺癌常通过大规模筛查被发现。本研究旨在评估通过大规模筛查发现的肺癌患者的治疗结果，并将其与因出现症状而被发现患有恶性肿瘤的患者进行比较。对截至1995年的20年间入住筑波大学医院呼吸内科的774例未经治疗的肺癌患者，根据其癌症发现原因进行了分析。在大规模筛查组（116例患者）中，50.0%的肺癌在TNM分期的I期被发现，而有症状的患者（561例患者）中只有8.2%患有I期肺癌（p = 0.0001）。由于通过大规模筛查发现的肺癌更常处于可手术阶段（I期、II期或IIIA期）（p = 0.0001），因此大规模筛查组更常选择手术治疗（p = 0.0001）。通过大规模筛查发现的肺癌患者的治疗结果比因症状发现的患者更有利（p = 0.0002）。通过大规模筛查早期发现肺癌有助于改善治疗结果。
