Queirolo P, Gipponi M, Peressini A, Raposio E, Vecchio S, Guenzi M, Sertoli M R, Santi P, Cafiero F
Department of Medical Oncology, University of Genoa, Italy.
Anticancer Res. 1997 May-Jun;17(3C):2339-42.
The clinical features of 10 cases of primary neuroendocrine carcinoma of the skin (Merker cell tumor) are reported. This cancer arises in the dermis and subcutaneous tissues of elderly individuals. Natural history is characterized by local recurrences (30%), regional lymph node metastases (65%) and distant metastases (40%). Surgery is elective treatment, chemotherapy and radiotherapy resulted only to short-term palliative response.
报告了10例原发性皮肤神经内分泌癌（默克尔细胞肿瘤）的临床特征。这种癌症发生在老年人的真皮和皮下组织中。其自然病程的特点是局部复发（30%）、区域淋巴结转移（65%）和远处转移（40%）。手术是选择性治疗方法，化疗和放疗仅产生短期姑息性反应。
