(1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor.
作者信息
Fung A K, Baker W R, Fakhoury S, Stein H H, Cohen J, Donner B G, Garvey D S, Spina K P, Rosenberg S H
机构信息
Aging and Degenerative Diseases Research, Pharmaceutical Discovery, Abbott Laboratories, Illinois 60064-3500, USA.
出版信息
J Med Chem. 1997 Jul 4;40(14):2123-5. doi: 10.1021/jm970058x.
PMID:9216829
Abstract
摘要
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(1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor.（1α，2β，3β，4α）-1,2-双[N-丙基-N-（4-苯氧基苄基）氨基甲酰基]环丁烷-3,4-二羧酸（A-87049）：一种新型强效角鲨烯合酶抑制剂。
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