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先天性中性粒细胞减少症患儿的骨矿化与骨转换及其与重组人粒细胞集落刺激因子治疗的关系。

Bone mineralization and turnover in children with congenital neutropenia, and its relationship to treatment with recombinant human granulocyte-colony stimulating factor.

作者信息

Fewtrell M S, Kinsey S E, Williams D M, Bishop N J

机构信息

MRC Dunn Nutrition Unit, Department of Paediatrics, Addenbrooke's Hospital, Cambridge.

出版信息

Br J Haematol. 1997 Jun;97(4):734-6. doi: 10.1046/j.1365-2141.1997.1302945.x.

DOI:10.1046/j.1365-2141.1997.1302945.x
PMID:9217170
Abstract

Bone mineral content (BMC) of the radius was measured using single photon absorptiometry (SPA) in nine children with congenital neutropenia. Five had normal values. Two children with severe congenital neutropenia (SCN) had low BMC, and two boys with Schwachman syndrome had biochemistry suggestive of rickets.

摘要

采用单光子吸收法（SPA）对9名先天性中性粒细胞减少症患儿的桡骨骨矿物质含量（BMC）进行了测量。其中5名患儿的值正常。2名严重先天性中性粒细胞减少症（SCN）患儿的BMC较低，2名施瓦赫曼综合征男孩的生化指标提示有佝偻病。

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Bone mineralization and turnover in children with congenital neutropenia, and its relationship to treatment with recombinant human granulocyte-colony stimulating factor.先天性中性粒细胞减少症患儿的骨矿化与骨转换及其与重组人粒细胞集落刺激因子治疗的关系。
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Severe osteopenia in a young boy with Kostmann's congenital neutropenia treated with granulocyte colony-stimulating factor: suggested therapeutic approach.用粒细胞集落刺激因子治疗的患有 Kostmann 先天性中性粒细胞减少症的小男孩出现严重骨质减少：建议的治疗方法。
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