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[塞尔维亚人群中HL - A抗原频率与P系统抗原之间的相关性]

[Correlation between the frequency of HL-A antigens and antigens of the P system in the population of Serbia].

作者信息

Gligorović V, Matejić T, Susaković N, Stolić I, Marković V

出版信息

Bilt Hematol Transfuz. 1977;5(1):3-11.

PMID:921730
Abstract

We studied the correlation between the antigens of the P system and the antigens and haplotypes of the HLA system in 334 nonrelated persons and 46 chosen families consisting of 166 members. On our material we found a distinct linear correlation between the antigens of the segregant serie A and especially of the segregant serie B and the P antigen of the blood groups. The correlation between the association of the antigens of series A and B and the antigens of the P system same as between the most frequent HLA haplotypes and the antigens of the P system, is also distinct. We described two cases of crossing over between the P and HLA system; the frequency of crossing over of 0,0435. We have confirmed the linkage between HLA and P and the likelihood that the genes are located on the same chromosome.

摘要

我们研究了334名非亲属个体以及46个选定家庭(共166名成员)中P系统抗原与HLA系统抗原及单倍型之间的相关性。基于我们的研究材料,我们发现分离系列A尤其是分离系列B的抗原与血型的P抗原之间存在明显的线性相关性。系列A和B抗原的组合与P系统抗原之间的相关性,与最常见的HLA单倍型和P系统抗原之间的相关性一样,也很明显。我们描述了两例P系统与HLA系统之间的交叉互换情况;交叉互换频率为0.0435。我们证实了HLA与P之间的连锁关系以及基因位于同一条染色体上的可能性。

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