转酮醇酶作用于亚硝基苯生成N-苯基甘醇羟肟酸。
N-phenylglycolhydroxamate production by the action of transketolase on nitrosobenzene.
作者信息
Corbett M D, Chipko B R
出版信息
Biochem J. 1977 Aug 1;165(2):263-7. doi: 10.1042/bj1650263.
Abstract
The incubation of nitrosobenzene with yeast transketolase and D-xylulose 5-phosphate resulted in the production of N-phenylglycolhydroxamic acid. The addition of D-ribose 5-phosphate decreased the amount of hydroxamic acid that was produced. This conversion of nitrosobenzene into the glycollic acid-derived hydroxamic acid was shown to be an enzymic process, and a chemical mechanism for the conversion was proposed.
摘要
亚硝基苯与酵母转酮醇酶和5-磷酸-D-木酮糖一起温育会产生N-苯基甘氨酸异羟肟酸。添加5-磷酸-D-核糖会减少所产生的异羟肟酸的量。已证明亚硝基苯向源自乙醇酸的异羟肟酸的这种转化是一个酶促过程，并提出了该转化的化学机制。
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