Allen P J, Downing J W
Br J Anaesth. 1977 Oct;49(10):1035-9. doi: 10.1093/bja/49.10.1035.
Ninety-nine Black females receiving radium therapy for carcinoma of the cervix uteri under either halothane (50 patients) or enflurane (49 patients) anaesthesia were studied. Thirty-six received a second and 13 a third exposure to halothane or enflurane. There were no significant changes from the control values in the serum concentrations of aspartate aminotransferase (s.g.o.t.), gamma glutamyl transpeptidase (gammaGT), lactic dehydrogenase (SLD), alkaline phosphatase (SAP) and proteins. Total serum bilirubin (TSB) decreased significantly during the first exposure to enflurane (P less than 0.01). This trend was reversed with subsequent anaesthetics in both the halothane and enflurane groups.
对99名接受子宫颈癌镭疗的黑人女性进行了研究，她们分别在氟烷（50例）或恩氟烷（49例）麻醉下接受治疗。36名患者接受了第二次、13名患者接受了第三次氟烷或恩氟烷暴露。天冬氨酸转氨酶（s.g.o.t.）、γ-谷氨酰转肽酶（γGT）、乳酸脱氢酶（SLD）、碱性磷酸酶（SAP）和蛋白质的血清浓度与对照值相比无显著变化。首次暴露于恩氟烷期间，总血清胆红素（TSB）显著下降（P<0.01）。在氟烷和恩氟烷组中，随着后续麻醉剂的使用，这种趋势发生了逆转。
