Eady R A, Gilkes J J, Jones E W
Br J Dermatol. 1977 Sep;97(3):267-78. doi: 10.1111/j.1365-2133.1977.tb15182.x.
The cases of two young adults with widespread multiple eruptive naevi are described. In the first patient, more than 100 lesions appeared during a period of 6 months. Young lesions were small flesh-coloured telangiectatic papules; older lesions were larger and verrucose with histological features of cellular naevi. In the second patient, a great number of lentigines developed in the course of 2 years. Light and electron microscopy showed that giant melanosomes were present within the lesions. The plasma level of beta-MSH-like immuno-reactivity was normal.
本文描述了两名患有广泛多发性发疹性痣的年轻成年人病例。在首例患者中,6个月内出现了100多个损害。早期损害为小的肉色毛细血管扩张性丘疹;晚期损害较大,呈疣状,具有细胞痣的组织学特征。在第二例患者中,2年内出现了大量雀斑样痣。光镜和电镜检查显示损害内存在巨大黑素小体。β-促黑素细胞激素样免疫反应性的血浆水平正常。