Adelstein P, Fedrick J, Howat P, Robinson R, Turnbull A C
Br J Obstet Gynaecol. 1977 Oct;84(10):721-5. doi: 10.1111/j.1471-0528.1977.tb12479.x.
A method is described of using matched pairs of index infants and controls to examine the hypothesis that induction or some other obstetric practice is associated with increased morbidity in the mature infant. All infants over 2250 g and 37 weeks gestation, without severe congenital defect or history of severe maternal disorder, born in the John Radcliffe and admitted to the Special Care Baby Unit in 1975 were identified. For each of these index infants a matched control was chosen using strict criteria. Contrast between the 109 matched pairs showed no significant differences between maternal characteristics, induction of labour, use of forceps or duration of labour. There was an excess of index infants born to mothers who had had epidural anaesthesia (P less than 0.05).
本文描述了一种方法,即使用配对的指数婴儿和对照婴儿来检验如下假设:引产或其他产科操作与成熟婴儿发病率增加有关。确定了1975年在约翰·拉德克利夫医院出生、体重超过2250克且妊娠37周以上、无严重先天性缺陷或严重母体疾病史并入住特殊护理婴儿病房的所有婴儿。对于每一名指数婴儿,都按照严格标准选择了一名配对对照。109对配对之间的对比显示,母体特征、引产、产钳使用或产程持续时间方面均无显著差异。接受硬膜外麻醉的母亲所生的指数婴儿数量过多(P<0.05)。