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人类胼胝体切开术后大脑特化的视觉诱发电位相关性

Visual evoked response correlates of cerebral specialization after human commissurotomy.

作者信息

Gott P S, Rossiter V S, Galbraith G C, Saul R E

出版信息

Biol Psychol. 1977 Sep;5(3):245-55. doi: 10.1016/0301-0511(77)90006-0.

DOI:10.1016/0301-0511(77)90006-0
PMID:922081
Abstract

Visual evoked responses (VERS) were recorded from commissurotomy patients and normal subjects in order to investigate the electrophysiological correlates of cerebral lateralization and independent hemispheric processing. A verbal task consisted of detecting rhyming words and a spatial task consisted of comparing matching shapes. Stimuli were delivered, by means of a computer graphic display, into the right visual field, the left visual field, or both visual fields. Behavioral results and evoked response waveforms showed lateralization for verbal processing in the left hemisphere for the patient group. Analysis of variance of product moment correlation coefficients between VER waveforms indicated significant differences between unilateral and bilateral stimulation for both patients and normals. Commissurotomy and normal VERs showed similar patterns of correlation when verbal stimuli were delivered to the left hemisphere, but differed during right hemisphere stimulation. The results are discussed in terms of VER correlates of visual-verbal processing.

摘要

为了研究大脑半球偏侧化和独立半球加工的电生理相关性,对连合部切开术患者和正常受试者进行了视觉诱发电位(VERS)记录。言语任务包括检测押韵词,空间任务包括比较匹配形状。通过计算机图形显示器将刺激分别呈现给右视野、左视野或双视野。行为结果和诱发电位波形显示,患者组在左半球进行言语加工时存在半球偏侧化。对VER波形之间的积矩相关系数进行方差分析表明,患者和正常人在单侧和双侧刺激之间存在显著差异。当言语刺激呈现给左半球时,连合部切开术患者和正常VERs显示出相似的相关模式,但在右半球刺激期间有所不同。根据视觉-言语加工的VER相关性对结果进行了讨论。

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