Grimfeld A
Hôpital d'Enfants Armand Trousseau, Service de Pédiatrie, Paris, France.
Allerg Immunol (Paris). 1997 Mar;29(3):73-4; discussion 82.
Given that the respiratory and immunity systems are still in development up to the age of 3 years, viral infections and exposure to environmental factors such as passive smoking in babies and young children may alter these systems, so favouring the development of allergic rhinitis and asthma. This may explain the correlation between viral respiratory infections or exposure to environmental factors and later development of wheezing and asthma. Prevention of respiratory infections may thus reduce the risks of pneumonopathy in the long term. For greatest efficacy however, the preventative measures must be in place before the age of 3 years, i.e. before lung development has been completed.
鉴于呼吸系统和免疫系统在3岁之前仍在发育中，病毒感染以及婴幼儿接触诸如被动吸烟等环境因素可能会改变这些系统，从而有利于过敏性鼻炎和哮喘的发展。这或许可以解释病毒呼吸道感染或接触环境因素与日后喘息和哮喘发展之间的关联。因此，预防呼吸道感染可能会长期降低肺病风险。然而，为了达到最大疗效，预防措施必须在3岁之前实施，即在肺部发育完成之前。
