来自基因不同的逆转录病毒的RNA可以在体内共同包装并交换遗传信息。
RNAs from genetically distinct retroviruses can copackage and exchange genetic information in vivo.
作者信息
Yin P D, Hu W S
机构信息
Department of Microbiology and Immunology, West Virginia University, Morgantown 26506, USA.
出版信息
J Virol. 1997 Aug;71(8):6237-42. doi: 10.1128/JVI.71.8.6237-6242.1997.
Abstract
Sequence analysis suggests that ancient recombination events may have occurred between genetically distinct retroviruses. An experimental system was utilized to explore the genetic interaction between different viruses. Moloney murine sarcoma virus and spleen necrosis virus are type C retroviruses that belong to different subgenera. With vectors containing packaging signals from these two viruses, DNA proviruses containing genetic information from both RNAs can be generated. This is the first experimental evidence to indicate that RNA from different retroviruses can copackage and exchange genetic information.
摘要
序列分析表明，古代重组事件可能发生在基因不同的逆转录病毒之间。利用一个实验系统来探索不同病毒之间的基因相互作用。莫洛尼鼠肉瘤病毒和脾坏死病毒是属于不同亚属的C型逆转录病毒。使用含有这两种病毒包装信号的载体，可以产生包含来自两种RNA遗传信息的DNA原病毒。这是表明来自不同逆转录病毒的RNA可以共同包装并交换遗传信息的首个实验证据。
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本文引用的文献
1
Improved retroviral packaging lines derived from spleen necrosis virus.
Virology. 1995 Apr 1;208(1):234-41. doi: 10.1006/viro.1995.1147.
2
Utilization of nonhomologous minus-strand DNA transfer to generate recombinant retroviruses.
J Virol. 1997 Mar;71(3):2487-94. doi: 10.1128/JVI.71.3.2487-2494.1997.
3
Efficient initiation and strand transfer of polypurine tract-primed plus-strand DNA prevent strand transfer of internally initiated plus-strand DNA.
J Virol. 1996 Mar;70(3):1687-94. doi: 10.1128/JVI.70.3.1687-1694.1996.
4
Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.
J Virol. 1993 Jul;67(7):3997-4005. doi: 10.1128/JVI.67.7.3997-4005.1993.
5
Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles.
J Virol. 1993 May;67(5):2681-8. doi: 10.1128/JVI.67.5.2681-2688.1993.
6
A double hairpin structure is necessary for the efficient encapsidation of spleen necrosis virus retroviral RNA.
EMBO J. 1994 Feb 1;13(3):713-26. doi: 10.1002/j.1460-2075.1994.tb06311.x.
7
Xenografting: probability, possibility, or pipe dream?
Lancet. 1993 Oct 9;342(8876):879-80. doi: 10.1016/0140-6736(93)91939-j.
8
Characterization of human immunodeficiency virus type 1 dimeric RNA from wild-type and protease-defective virions.
J Virol. 1994 Aug;68(8):5013-8. doi: 10.1128/JVI.68.8.5013-5018.1994.
9
Retroviral RNA packaging: a review.
Arch Virol Suppl. 1994;9:513-22. doi: 10.1007/978-3-7091-9326-6_49.
10
Barriers to xenotransplantation.
Nat Med. 1995 Sep;1(9):869-73. doi: 10.1038/nm0995-869.
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