Xin Z C, Choi Y D, Rha K H, Choi H K
Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
J Urol. 1997 Aug;158(2):451-5.
Premature ejaculation has been believed to be psychological in the majority of patients. With few exceptions organic conditions are rarely implicated. We investigated the possible role of sensory function in patients with primary premature ejaculation to determine whether there is an etiological basis for this condition.
We performed somatosensory evoked potentials from the penis in 34 patients with primary premature ejaculation and in 30 normally potent men. The latencies and amplitudes of the evoked potentials were measured at the penile shaft (dorsal nerve) and at the glans penis.
Mean latency of dorsal nerve and glans penis somatosensory evoked potentials was 1.51 and 6.80 (significant) msec. shorter, respectively, in the patients than in the normal subjects. In the normal subjects the mean latency of glans penis somatosensory evoked potentials was 0.99 msec. longer than that of the dorsal nerve (not significantly different) but in patients the mean latency in the glans penis was 4.30 msec. shorter (p < 0.001). Mean amplitude of glans penis somatosensory evoked potentials was less than that of the dorsal nerve in both groups. However, mean amplitudes of dorsal nerve and glans penis somatosensory evoked potentials were significantly greater in patients than in normal men.
Patients with premature ejaculation have hypersensitivity and hyperexcitability of the glans penis, which may give rise to uncontrolled ejaculation and are believed to be organic implications for premature ejaculation.
大多数早泄患者被认为存在心理因素。除少数例外，很少涉及器质性疾病。我们研究了原发性早泄患者感觉功能的可能作用，以确定这种情况是否存在病因学基础。
我们对34例原发性早泄患者和30例性功能正常的男性进行了阴茎体感诱发电位检查。在阴茎体（背神经）和阴茎头测量诱发电位的潜伏期和波幅。
早泄患者阴茎体和阴茎头体感诱发电位的平均潜伏期分别比正常受试者短1.51和6.80（显著）毫秒。在正常受试者中，阴茎头体感诱发电位的平均潜伏期比背神经长0.99毫秒（无显著差异），但在早泄患者中，阴茎头的平均潜伏期短4.30毫秒（p<0.001）。两组中阴茎头体感诱发电位的平均波幅均低于背神经。然而，早泄患者背神经和阴茎头体感诱发电位的平均波幅明显高于正常男性。
早泄患者阴茎头存在超敏性和兴奋性过高，这可能导致无法控制的射精，被认为是早泄的器质性因素。
