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原发性早泄患者龟头和阴茎干的敏感性差异。

The sensitivity difference between the glans penis and penile shaft in primary premature ejaculation.

机构信息

Department of Andrology, Second Hospital of Dalian Medical University, Dalian 116000, China.

Department of Urology, First Hospital of Dalian Medical University, Dalian 116000, China.

出版信息

Asian J Androl. 2023;25(4):487-491. doi: 10.4103/aja2022120.

DOI:10.4103/aja2022120
PMID:36861504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10411261/
Abstract

The penis is a vital organ of perception that transmits perceived signals to ejaculation-related centers. The penis consists of the glans penis and penile shaft, which differ considerably in both histology and innervation. This paper aims to investigate whether the glans penis or the penile shaft is the main source of sensory signals from the penis and whether penile hypersensitivity affects the whole organ or only part of it. The thresholds, latencies, and amplitudes of somatosensory evoked potentials (SSEPs) were recorded in 290 individuals with primary premature ejaculation using the glans penis and penile shaft as the sensory areas. The thresholds, latencies, and amplitudes of SSEPs from the glans penis and penile shaft in patients were significantly different (all P < 0.0001). The latency of the glans penis or penile shaft was shorter than average (indicating hypersensitivity) in 141 (48.6%) cases, of which 50 (35.5%) cases were sensitive in both the glans penis and penile shaft, 14 (9.9%) cases were sensitive in the glans penis only, and 77 (54.6%) cases were sensitive in the penile shaft only (P < 0.0001). There are statistical differences in the signals perceived through the glans penis and the penile shaft. Penile hypersensitivity does not necessarily mean that the whole penis is hypersensitive. We classify penile hypersensitivity into three categories, namely, glans penis, penile shaft, and whole-penis hypersensitivity, and we propose the new concept of penile hypersensitive zone.

摘要

阴茎是感知的重要器官,可将感知信号传输到与射精相关的中枢。阴茎由龟头和阴茎干组成,在组织学和神经支配上有很大的不同。本文旨在探讨龟头和阴茎干哪个是阴茎感觉信号的主要来源,以及阴茎高敏感是否影响整个器官或仅影响部分器官。使用龟头和阴茎干作为感觉区域,对 290 例原发性早泄患者进行躯体感觉诱发电位(SSEP)的阈值、潜伏期和振幅记录。患者的龟头和阴茎干的 SSEP 阈值、潜伏期和振幅差异均有统计学意义(均 P < 0.0001)。141 例(48.6%)的龟头或阴茎干潜伏期短于平均值(提示高敏感),其中 50 例(35.5%)龟头和阴茎干均敏感,14 例(9.9%)龟头敏感,77 例(54.6%)阴茎干敏感(P < 0.0001)。通过龟头和阴茎干感知的信号存在统计学差异。阴茎高敏感并不一定意味着整个阴茎都敏感。我们将阴茎高敏感分为龟头、阴茎干和整个阴茎高敏感三类,并提出了阴茎高敏感区的新概念。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/9a74c96752ab/AJA-25-487-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/133ca9529382/AJA-25-487-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/c292ab6eac88/AJA-25-487-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/9a74c96752ab/AJA-25-487-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/133ca9529382/AJA-25-487-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/c292ab6eac88/AJA-25-487-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/10411261/9a74c96752ab/AJA-25-487-g003.jpg

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The Diagnostic Role of Neurophysiological Tests for Premature Ejaculation: A Prospective Multicenter Study.神经生理测试对早泄的诊断作用:一项前瞻性多中心研究。
J Urol. 2022 Jan;207(1):172-182. doi: 10.1097/JU.0000000000002198. Epub 2021 Aug 30.
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Sensory innervation of the human male prepuce: Meissner's corpuscles predominate.人类男性包皮的感觉神经支配:梅克尔氏小体占主导地位。
J Anat. 2021 Oct;239(4):892-902. doi: 10.1111/joa.13481. Epub 2021 Jun 12.
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A Study of Differences in Penile Dorsal Nerve Somatosensory Evoked Potential Testing Among Healthy Controls and Patients With Primary and Secondary Premature Ejaculation.
原发性和继发性早泄患者与健康对照者阴茎背神经躯体感觉诱发电位检测的差异研究。
J Sex Med. 2021 Apr;18(4):732-736. doi: 10.1016/j.jsxm.2021.01.186. Epub 2021 Mar 18.
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Is mild erectile dysfunction associated with severe psychological symptoms in Chinese patients with moderate-to-severe chronic prostatitis/chronic pelvic pain syndrome?在中国患有中重度慢性前列腺炎/慢性盆腔疼痛综合征的患者中,轻度勃起功能障碍是否与严重的心理症状相关?
Asian J Androl. 2021 May-Jun;23(3):319-324. doi: 10.4103/aja.aja_71_20.
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Macro/microscopic distribution of the dorsal nerve of penis in human glans penis.阴茎龟头背神经的宏观/微观分布。
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Regular penis-root masturbation, a novel behavioral therapy in the treatment of primary premature ejaculation.常规阴茎根部自慰,一种治疗原发性早泄的新型行为疗法。
Asian J Androl. 2019 Nov-Dec;21(6):631-634. doi: 10.4103/aja.aja_34_19.
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Sci Rep. 2017 Sep 5;7(1):10441. doi: 10.1038/s41598-017-09155-8.
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