Yeatts R P, White W L
Department of Ophthalmology, Bowman Gray School of Medicine of Wake Forest University Winston-Salem, North Carolina, USA.
Ophthalmology. 1997 Jul;104(7):1185-9; discussion 1189-90. doi: 10.1016/s0161-6420(97)30390-x.
The objective of our study was to describe the ophthalmic features and histologic eyelid findings of Melkersson-Rosenthal syndrome.
Three patients with eyelid edema underwent eyelid biopsy to establish the diagnosis of Melkersson-Rosenthal syndrome.
Of the three patients, only one patient manifest the classic triad of facial edema, facial paralysis, and furrowed tongue. Histoloppgically, the eyelid skin in all patients showed characteristic perilymphatic granulomas with marked dermal edema.
The histopathologic features assist in establishing the diagnosis of Melkersson-Rosenthal syndrome in oligo- and monosymptomatic patients. Melkersson-Rosenthal syndrome should be considered in patients presenting with eyelid edema of unknown etiology and biopsy performed.
我们研究的目的是描述梅尔克森 - 罗森塔尔综合征的眼科特征和眼睑组织学表现。
三名眼睑水肿患者接受了眼睑活检以确诊梅尔克森 - 罗森塔尔综合征。
三名患者中，只有一名表现出面部水肿、面瘫和皱襞舌的典型三联征。组织学上，所有患者的眼睑皮肤均显示特征性的淋巴管周围肉芽肿伴明显的真皮水肿。
组织病理学特征有助于在症状较少和单一症状的患者中确诊梅尔克森 - 罗森塔尔综合征。对于病因不明的眼睑水肿患者应考虑梅尔克森 - 罗森塔尔综合征并进行活检。
