Wilson J R, Webb S V, Sherman S M
Brain Res. 1977 Nov 11;136(2):277-87. doi: 10.1016/0006-8993(77)90803-4.
Three groups of visually deprived cats were studied for evidence that one eye gained a competitive advantage over the other during development of central connections. We attempted to detect such an advantage by measuring lateral geniculate cell sizes, by recording the proportion of lateral geniculate Y-cells and the ocular dominance of cortical neurons, and/or by testing visual orienting behavior. Three cats were raised with one eye covered by the lids, and the other, by the nictitating membrane. Lids reduce illumination by 3--4 log units, nictitating membranes, by about one log unit, and both eliminate spatial patterns. Neither eye in these cats appeared to develop with a competitive advantage over the other. Four cats raised with monocular nictitating membrane closure developed with a clear advantage to the open eye, and in all ways data from these cats were indistinguishable from those previously reported for monocularly lid sutured cats. Finally, 4 cats reared with binocular lid closure, but with additional, temporally modulated stimulation through the right lids, showed no evidence of a competitive advantate to either eye. We conclude that interocular differences in light intensity or temporal patterns do not confer a significant competitive advantage to either eye during development of central connections.
对三组视觉剥夺猫进行了研究，以寻找在中枢连接发育过程中一只眼睛相对于另一只眼睛获得竞争优势的证据。我们试图通过测量外侧膝状体细胞大小、记录外侧膝状体Y细胞的比例和皮质神经元的眼优势，和/或通过测试视觉定向行为来检测这种优势。三只猫在成长过程中，一只眼睛被眼睑覆盖，另一只眼睛被瞬膜覆盖。眼睑可使光照降低3 - 4个对数单位，瞬膜可使光照降低约1个对数单位，二者都会消除空间模式。这些猫的两只眼睛在发育过程中似乎都没有相对于另一只眼睛的竞争优势。四只在成长过程中接受单眼瞬膜闭合处理的猫，睁开的眼睛明显占优势，并且从各方面来看，这些猫的数据与之前报道的单眼眼睑缝合猫的数据没有区别。最后，四只在成长过程中双眼睑闭合，但通过右侧眼睑进行额外的、随时间调制的刺激的猫，没有显示出任何一只眼睛具有竞争优势的证据。我们得出结论，在中枢连接发育过程中，眼间光强度或时间模式的差异不会赋予任何一只眼睛显著的竞争优势。
