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清醒猫全身性青霉素癫痫发作时的神经元放电模式。

Neuronal firing patterns during generalized penicillin epilepsy in the awake cat.

作者信息

Wray D V, Hablitz J J

出版信息

Brain Res Bull. 1977 Sep-Oct;2(5):317-21. doi: 10.1016/0361-9230(77)90065-x.

DOI:10.1016/0361-9230(77)90065-x
PMID:922510
Abstract

Single unit activity was recorded in the neocortex of awake cats during spontaneous spike wave discharges. Ongoing activity was interrupted during paroxysmal events and was replaced by (1) bursts of action potentials coincident with the EEG spike and cessation of firing during the wave, or (2) cessation of firing for the duration of the paroxysm. Other units which displayed little or no background activity were recruited to fire during the EEG spike. Surface cerebellar stimulation at high frequencies led to decreased neuronal activity while single pulse shocks resulted in short latency activation. These results were compared to studies of spike wave activity elicited by electrical stimulation.

摘要

在清醒猫的新皮层中记录自发棘波放电期间的单单位活动。阵发性事件期间,持续活动被打断,并被以下情况取代:(1) 与脑电图棘波同时出现的动作电位爆发,以及波期间放电停止;或者 (2) 在发作期间放电停止。其他几乎没有背景活动或没有背景活动的单位在脑电图棘波期间被募集放电。高频刺激小脑表面导致神经元活动减少,而单脉冲电击则导致短潜伏期激活。将这些结果与电刺激引发的棘波活动研究进行了比较。

相似文献

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Neuronal firing patterns during generalized penicillin epilepsy in the awake cat.清醒猫全身性青霉素癫痫发作时的神经元放电模式。
Brain Res Bull. 1977 Sep-Oct;2(5):317-21. doi: 10.1016/0361-9230(77)90065-x.
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Effects of changes in cortical excitability upon the epileptic bursts in generalized penicillin epilepsy of the cat.皮质兴奋性变化对猫全身性青霉素癫痫发作中癫痫样放电的影响。
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Chronically isolated cerebral hemisphere in the cat: effects of parenteral administration of penicillin.猫的慢性孤立大脑半球:肠胃外注射青霉素的影响
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Differential participation of some 'specific' and 'non-specific' thalamic nuclei in generalized spike and wave discharges of feline generalized penicillin epilepsy.某些“特异性”和“非特异性”丘脑核在猫全身性青霉素癫痫的全身性棘波和慢波放电中的不同参与情况。
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Dynamic coupling among neocortical neurons during evoked and spontaneous spike-wave seizure activity.诱发性和自发性棘波-慢波癫痫发作活动期间新皮层神经元之间的动态耦合。
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Spike-wave rhythms in cat cortex induced by parenteral penicillin. I. Electroencephalographic features.肠胃外注射青霉素诱发猫皮层的棘波节律。I. 脑电图特征。
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An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons.利用皮层和丘脑单个神经元同步记录对青霉素诱导的全身性棘波和慢波放电进行分析。
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Involvement of cortical, thalamic and midbrain reticular formation neurons in spike and wave discharges: extracellular study in feline generalized penicillin epilepsy.皮质、丘脑及中脑网状结构神经元在棘波和慢波放电中的作用:猫全身性青霉素癫痫的细胞外研究
Exp Neurol. 1985 Aug;89(2):465-78. doi: 10.1016/0014-4886(85)90106-2.

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