aged garlic extract及其成分可抑制Cu(2+)诱导的低密度脂蛋白氧化修饰。 （注：这里“aged garlic extract”常见释义为“ aged garlic extract”，但在医学专业语境中可能有更准确的特定译名，比如“陈蒜提取物”等，你可根据实际专业情况调整。）
Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein.
作者信息
Ide N, Nelson A B, Lau B H
出版信息
Planta Med. 1997 Jun;63(3):263-4. doi: 10.1055/s-2006-957668.
Oxygen radical injury and lipid peroxidation have been suggested as major causes of atherosclerosis, cancer, liver disease, and the aging process. More specifically, oxidative modification of low density lipoprotein (LDL) has been recognized as an important process of atherosclerosis. In this study, we determined the effects of aged garlic extract (AGE), four of its constituents, and a metabolite on Cu(2+)-induced oxidative modification of LDL using an in vitro system. All these compounds were shown to inhibit oxidative modification of LDL.
氧自由基损伤和脂质过氧化被认为是动脉粥样硬化、癌症、肝脏疾病及衰老过程的主要原因。更具体地说，低密度脂蛋白（LDL）的氧化修饰已被公认为是动脉粥样硬化的一个重要过程。在本研究中，我们使用体外系统确定了 aged garlic extract（AGE）、其四种成分及一种代谢产物对铜离子（Cu(2+)）诱导的LDL氧化修饰的影响。所有这些化合物均显示出能抑制LDL的氧化修饰。
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