Singh G, Krause J R, Breitfeld V
Cancer. 1977 Nov;40(5):2317-21. doi: 10.1002/1097-0142(197711)40:5<2317::aid-cncr2820400546>3.0.co;2-z.
A 6-year experience with bone marrow aspirates and biopsies (96 cases) positive for metastatic carcinoma is reviewed. Marrow examination detected secondary carcinoma in 58 cases (60%) despite negative roentgenographic and/or bone scan examinations. Breast carcinoma was the most frequent primary site. The bone marrow biopsy was superior to the aspirate in finding carcinoma (97% vs. 72%). However, in an occasional case, tumor was found only in aspirate preparations. Both procedures should be considered complementary and are recommended in the marrow evaluation of patients with carcinoma.
回顾了6年中96例骨髓穿刺和活检发现转移性癌阳性的病例。尽管X线和/或骨扫描检查结果为阴性，但骨髓检查仍在58例（60%）中检测到继发性癌。乳腺癌是最常见的原发部位。在发现癌方面，骨髓活检优于骨髓穿刺（97%对72%）。然而，偶尔也有病例仅在穿刺涂片标本中发现肿瘤。两种检查方法应被视为互补，建议在癌患者的骨髓评估中同时采用。
