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2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.

作者信息

Lin J K, Miller J A, Miller E C

出版信息

Cancer Res. 1977 Dec;37(12):4430-8.

PMID:922734
Abstract
摘要

相似文献

1
2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.2,3-二氢-2-（鸟嘌呤-7-基）-3-羟基黄曲霉毒素B1，是在肝微粒体介导的反应以及大鼠肝脏体内形成的黄曲霉毒素B1-DNA或-核糖体RNA加合物的主要酸水解产物。
Cancer Res. 1977 Dec;37(12):4430-8.
2
Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.黄曲霉毒素B1 - 2,3 - 环氧化物可能是黄曲霉毒素B1和B2在体内与大鼠肝脏DNA和核糖体RNA共价结合的中间体。
Cancer Res. 1977 Jan;37(1):172-81.
3
Quantitative and qualitative characterization of aflatoxin B1 adducts formed in vivo within the ribosomal RNA genes of rat liver DNA.大鼠肝脏DNA核糖体RNA基因体内形成的黄曲霉毒素B1加合物的定量和定性表征。
Cancer Res. 1985 Aug;45(8):3497-502.
4
Quantitative comparison of covalent aflatoxin-DNA adducts formed in rat and mouse livers and kidneys.大鼠和小鼠肝脏及肾脏中形成的共价黄曲霉毒素 - DNA 加合物的定量比较。
J Natl Cancer Inst. 1981 Apr;66(4):761-8.
5
Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes.肝微粒体将黄曲霉毒素B1还原为2,3-二氢-2,3-二羟基黄曲霉毒素B1的烟酰胺腺嘌呤二核苷酸磷酸依赖性形成过程。
Cancer Res. 1978 Aug;38(8):2424-8.
6
Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon.黄曲霉毒素B1的代谢及在培养的人支气管和结肠中形成的主要黄曲霉毒素B1-DNA加合物的鉴定。
Cancer Res. 1979 Mar;39(3):694-8.
7
The reactivity and carcinogenicity of aflatoxin B1-2,3-dichloride, a model for the putative 2,3-oxide metabolite of aflatoxin B1.黄曲霉毒素B1 - 2,3 - 二氯化合物的反应活性和致癌性，黄曲霉毒素B1假定的2,3 - 氧化物代谢物的模型。
Cancer Res. 1975 Dec;35(12):3811-23.
8
Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1.单次及多次给予黄曲霉毒素B1后大鼠肝脏中共价DNA加合物的时间模式。
Cancer Res. 1981 Jan;41(1):197-203.
9
N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo.鸟嘌呤的N2原子和腺嘌呤残基的N6原子作为体内代谢活化的1'-羟基黄樟素与小鼠肝脏DNA共价结合的位点。
Cancer Res. 1981 Jul;41(7):2664-71.
10
Effect of sex difference on the in vitro and in vivo metabolism of aflatoxin B1 by the rat.性别差异对大鼠体内外黄曲霉毒素B1代谢的影响。
Cancer Res. 1976 Dec;36(12):4663-71.

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Accurate Identification of Degraded Products of Aflatoxin B Under UV Irradiation Based on UPLC-Q-TOF-MS/MS and NMR Analysis.基于超高效液相色谱-四极杆飞行时间串联质谱（UPLC-Q-TOF-MS/MS）和核磁共振（NMR）分析对黄曲霉毒素B在紫外照射下的降解产物进行准确鉴定
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Genome Profiling for Aflatoxin B Resistance in Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B-Associated DNA Damage.揭示了 CSM2/SHU 复合物在耐受与黄曲霉毒素 B 相关的 DNA 损伤中的作用。
G3 (Bethesda). 2020 Nov 5;10(11):3929-3947. doi: 10.1534/g3.120.401723.
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Mode of action-based risk assessment of genotoxic carcinogens.基于作用模式的遗传毒性致癌物风险评估。
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Aflatoxin B₁⁻Formamidopyrimidine DNA Adducts: Relationships between Structures, Free Energies, and Melting Temperatures.黄曲霉毒素 B₁⁻甲酰胺嘧啶 DNA 加合物：结构、自由能和熔点之间的关系。
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