Nelson J C
Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. 06520-8037, USA.
J Clin Psychiatry. 1997;58 Suppl 6:26-31.
The newer serotonergic antidepressants have become popular particularly because of improved tolerability and safety. The evidence supporting this belief is reviewed. The factors that contribute to the development of somatic symptoms are examined, including the depression itself and the drugs used for treatment. The rates for individual side effects with the serotonin selective reuptake inhibitors, nefazodone, and venlafaxine are presented and compared with the adverse event experience for mirtazapine.
新型的血清素能抗抑郁药尤其因耐受性和安全性的提高而受到欢迎。本文回顾了支持这一观点的证据。研究了导致躯体症状出现的因素，包括抑郁症本身以及用于治疗的药物。列出了血清素选择性再摄取抑制剂、奈法唑酮和文拉法辛的个体副作用发生率，并与米氮平的不良事件情况进行了比较。
