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持续气道正压通气(CPAP)疗法在急性重症心源性肺水肿急救管理中的应用经验。

Experience with the use of continuous positive airway pressure (CPAP) therapy in the emergency management of acute severe cardiogenic pulmonary oedema.

作者信息

Kelly A M, Georgakas C, Bau S, Rosengarten P

机构信息

Western Hospital, Melbourne, Vic.

出版信息

Aust N Z J Med. 1997 Jun;27(3):319-22. doi: 10.1111/j.1445-5994.1997.tb01985.x.

Abstract

BACKGROUND

Acute pulmonary oedema (APO) is a frequent cause of respiratory failure and a common reason for presentation to emergency departments (EDs). To date, no paper has been published on the application of continuous positive airway pressure (CPAP) therapy for a large broad-based patient group.

AIM

To report our experience with the use of CPAP in severe APO oedema, with particular reference to safety, intubation rates and impact on EDs' resources.

METHOD

A retrospective chart review was undertaken of 75 patients with acute severe pulmonary oedema who were treated with adjuvant CPAP in an urban teaching hospital ED.

RESULTS

Three patients (4%) required subsequent endotracheal intubation and mechanical ventilation. The average duration of CPAP was 1.9 hours. Eighty nine per cent of patients experienced no adverse events while being treated with GPAP. Five patients failed to tolerate the tight fitting mask necessitating removal of CPAP, three patients experienced arrhythmias related to underlying cardiac disease and two patients experienced mild transient hypotension. Seventy one per cent of patients were discharged from the ED to general medical wards. The in-hospital mortality for patients treated with CPAP was 15%.

CONCLUSION

This series has demonstrated that CPAP therapy delivered via a face mask for the treatment of acute severe APO is safe and effective when applied to a broad range of patients. We recommend the use of CPAP therapy for all suitable patients presenting in severe APO irrespective of age or underlying pulmonary disease.

摘要

背景

急性肺水肿(APO)是呼吸衰竭的常见病因,也是急诊室(ED)就诊的常见原因。迄今为止,尚未有关于持续气道正压通气(CPAP)疗法应用于广泛患者群体的论文发表。

目的

报告我们在重度APO水肿中使用CPAP的经验,特别提及安全性、插管率以及对急诊室资源的影响。

方法

对一家城市教学医院急诊科75例接受辅助CPAP治疗的急性重度肺水肿患者进行回顾性病历审查。

结果

3例患者(4%)随后需要气管插管和机械通气。CPAP的平均使用时间为1.9小时。89%的患者在接受CPAP治疗时未出现不良事件。5例患者无法耐受紧密贴合的面罩,因此需要移除CPAP;3例患者出现与基础心脏病相关的心律失常;2例患者出现轻度短暂性低血压。71%的患者从急诊科出院后转入普通内科病房。接受CPAP治疗患者的院内死亡率为15%。

结论

本系列研究表明,通过面罩进行CPAP治疗急性重度APO应用于广泛患者群体时是安全有效的。我们建议对所有因重度APO就诊的合适患者使用CPAP治疗,无论其年龄或基础肺部疾病如何。

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