Hall H D, Schneyer C A
Cell Tissue Res. 1977 Oct 26;184(2):249-54. doi: 10.1007/BF00223072.
The role of functional activity in mediating compensatory enlargement of the parotid gland after removal of the other major salivary glands was investigated. Increased levels of activity were achieved by feeding rats a bulk diet. Conversely, a liquid diet was used to reduce the functional demands on the parotid. It was found that the liquid diet completely prevented the compensatory response from occurring. Bulk diet, on the other hand, caused an even greater compensatory response than did the standard chow diet. Compensatory enlargement of the parotid, therefore, depends on its functional activity and not on other, e.g., humoral factors dissociated from function. The character of the cellular response in compensatory enlargement was also examined. The chow diet caused compensatory enlargement by an increase in cell size with little, if any, increase in cell number.
研究了功能活动在介导其他主要唾液腺切除后腮腺代偿性增大中的作用。通过给大鼠喂食大量食物来提高活动水平。相反，使用流质饮食来降低腮腺的功能需求。结果发现，流质饮食完全阻止了代偿反应的发生。另一方面，大量食物饮食比标准普通饲料饮食引起的代偿反应更大。因此，腮腺的代偿性增大取决于其功能活动，而不取决于其他因素，例如与功能无关的体液因素。还检查了代偿性增大中细胞反应的特征。普通饲料饮食通过细胞大小增加而引起代偿性增大，细胞数量即使有增加也很少。
