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大鼠腮腺代偿性肿大的神经调节

Neural regulation of compensatory enlargement of the parotid gland of the rat.

作者信息

Hall H D, Schneyer C A

出版信息

Cell Tissue Res. 1978 Feb 14;187(1):147-51. doi: 10.1007/BF00220626.

DOI:10.1007/BF00220626
PMID:630587
Abstract

The role of the innervation in mediating compensatory enlargement of the parotid gland of the rat after partial desalivation was examined. The results of denervation experiments show that full compensatory growth requires both parasympathetic and sympathetic innervation. The presence of the parasympathetic innervation alone results in an increase in the number of cells, but not the size of the cells. The sympathetic innervation alone does not mediate either response. We, therefore, conclude that the two types of innervation have a synergistic action on the parotid to produce the maximal compensatory response, which includes an increase in both number and size of acinar cells.

摘要

研究了去神经支配在介导大鼠部分唾液分泌减少后腮腺代偿性肿大中的作用。去神经支配实验结果表明,完全代偿性生长需要副交感神经和交感神经的双重支配。仅存在副交感神经支配会导致细胞数量增加,但细胞大小不变。单独的交感神经支配不会介导这两种反应。因此,我们得出结论,这两种神经支配对腮腺具有协同作用,以产生最大的代偿反应,其中包括腺泡细胞数量和大小的增加。

相似文献

1
Neural regulation of compensatory enlargement of the parotid gland of the rat.大鼠腮腺代偿性肿大的神经调节
Cell Tissue Res. 1978 Feb 14;187(1):147-51. doi: 10.1007/BF00220626.
2
Effects of denervation on development of function and structure of immature rat parotid.去神经支配对未成熟大鼠腮腺功能和结构发育的影响。
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3
Effect of parasympathetic denervation on acetylcholine levels in the rat parotid gland. Is there an extraneuronal pool of acetylcholine?
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Non-adrenergic, non-cholinergic influences on parotid acinar degranulation in response to stimulation of the parasympathetic innervation in the anaesthetized rat.非肾上腺素能、非胆碱能因素对麻醉大鼠腮腺腺泡在副交感神经支配刺激下脱颗粒的影响。
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Acquisition of cholinergic and peptidergic properties by sympathetic innervation of rat sweat glands requires interaction with normal target.大鼠汗腺的交感神经支配获得胆碱能和肽能特性需要与正常靶组织相互作用。
Neuron. 1990 Jul;5(1):91-100. doi: 10.1016/0896-6273(90)90037-g.

引用本文的文献

1
Cell surface expression of 4 beta-galactosyltransferase accompanies rat parotid gland hypertrophy induced by changes in diet.4-β-半乳糖基转移酶的细胞表面表达伴随饮食变化诱导的大鼠腮腺肥大。
Biochem J. 1987 Sep 1;246(2):387-91. doi: 10.1042/bj2460387.
2
Cell surface galactosyltransferase acts as a general modulator of rat acinar cell proliferation.
Mol Cell Biochem. 1990 Jun 1;95(1):1-11. doi: 10.1007/BF00219524.

本文引用的文献

1
Determination of nucleic acids in animal tissues.动物组织中核酸的测定。
J Biol Chem. 1955 May;214(1):59-70.
2
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.用于比色法测定脱氧核糖核酸的二苯胺反应的条件及机制研究。
Biochem J. 1956 Feb;62(2):315-23. doi: 10.1042/bj0620315.
3
Functional hypertrophy and atrophy of the salivary glands of rats.大鼠唾液腺的功能性肥大与萎缩
Am J Physiol. 1967 Feb;212(2):247-51. doi: 10.1152/ajplegacy.1967.212.2.247.
4
Function of rat parotid gland after sympathectomy and total postganglionectomy.大鼠交感神经切除和节后神经全切除后腮腺的功能
Am J Physiol. 1966 Oct;211(4):943-9. doi: 10.1152/ajplegacy.1966.211.4.943.
5
Role of autonomic pathways in disuse atrophy of rat parotid.
Proc Soc Exp Biol Med. 1973 May;143(1):19-23. doi: 10.3181/00379727-143-37244.
6
Functional mediation of compensatory enlargement of the parotid gland.腮腺代偿性肿大的功能介导
Cell Tissue Res. 1977 Oct 26;184(2):249-54. doi: 10.1007/BF00223072.