Malleson P N, Petty R E
British Columbia's Children's Hospital, Vancouver, Canada.
Curr Opin Rheumatol. 1997 Jul;9(4):291-4. doi: 10.1097/00002281-199707000-00003.
Relatively little is written about the juvenile spondyloarthropathies. The literature of the past year has included data on the frequency of juvenile spondyloarthropathies, which indicate that these are almost certainly a more common form of childhood arthropathy than formerly believed. Although clinical differences exist between juvenile spondyloarthropathies and juvenile rheumatoid arthritis, there is only limited information about differences in the pathophysiology of these diseases. One study suggests some differences in the expression of tumor necrosis factor and its receptors. Evidence also presented this year suggests that juvenile psoriatic arthritis is probably a separate condition from the spondyloarthropathies. It is hoped that better understanding of the epidemiology and pathophysiology of the juvenile spondyloarthropathies will lead to better treatment strategies.
关于青少年脊柱关节病的文献相对较少。过去一年的文献中有关于青少年脊柱关节病发病率的数据，这些数据表明，几乎可以肯定，青少年脊柱关节病是一种比以前认为的更为常见的儿童关节病形式。尽管青少年脊柱关节病与青少年类风湿性关节炎之间存在临床差异，但关于这些疾病病理生理学差异的信息有限。一项研究表明肿瘤坏死因子及其受体的表达存在一些差异。今年提出的证据还表明，青少年银屑病关节炎可能是一种与脊柱关节病不同的疾病。希望对青少年脊柱关节病的流行病学和病理生理学有更好的了解将带来更好的治疗策略。
