Ruwart M J, Henley K S
The Upjohn Company, Kalamazoo, Michigan, USA.
Gastroenterol Clin North Am. 1996 Jun;25(2):397-407. doi: 10.1016/s0889-8553(05)70254-5.
This brief review summarizes the physiology and pharmacology of eicosanoids and describes how they have been tested for possible application in liver disease and transplantation. The objective is to trace the stepwise application from the laboratory to the bedside. Although many questions remain to be answered, the observations summarized in this article have opened up new and potentially rewarding prospects in application to liver disease.
本简要综述总结了类二十烷酸的生理学和药理学,并描述了它们在肝病和移植中可能的应用是如何进行测试的。目的是追溯从实验室到床边的逐步应用过程。尽管仍有许多问题有待解答,但本文总结的观察结果为肝病应用开辟了新的、潜在有益的前景。