Menzel M, Soukup J, Rieger A, Roth S, Radke J, Burkert W
Klinik für Anästhesiologie und operative Intensivmedizin de Martin-Luther-Universität Halle-Wittenberg.
Anaesthesist. 1997 Apr;46(4):329-34. doi: 10.1007/s001010050407.
Recently, a compact multisensor device 0.5 mm in diameter has become available with a miniaturised Clark electrode for measuring blood oxygen tension and two optical fibres for measuring CO2 tension, pH, and temperature (Paratrend 7, Biomedical Sensors, High Wycombe, UK). We used this new probe for continuous blood gas monitoring in the jugular bulb as an alternative to the commonly used fiberoptic spectrophotometric oximetric measurement of haemoglobin saturation.
A 64-year-old patient was admitted for surgery of a right-sided intracranial aneurysm. During surgery, with no artefacts or evidence of catheter drift, a normal jugular venous pO2 (pjvO2) of 39 +/- 3 mmHg was measured. Over the period of weaning, two declines in pjvO2 occurred (22.5 and 18.7 mm Hg) associated with a decline in CO2 tension and a rise in pH. We treated these events successfully by analgosedation, controlled ventilation with an inspired oxygen fraction of 70%, and elevation of the mean arterial blood pressure to over 100 mmHg. Extubation was possible about 24 h later. Furthermore, 3 h after extubation pjvO2 values could be monitored without difficulty despite movement of the patient.
The technique of polarographically measuring pjvO2 with a Clark-type probe appears superior to fibreoptic jugular venous oximetry due to the clearly lower incidence of faulty measurements, especially in the intensive care unit, where patients undergo frequent nursing interventions and tend to awaken. We did not even observe artefacts due to patient movement after extubation. A limitation of the new multisensor system might be the distance of 4 cm between the sensor tip and the end of the insertion catheter, which makes samples drawn for in vitro blood gas analyses to control the continuous monitoring less comparable. Improvements in the construction of the probe are recommended.
最近,一种直径为0.5毫米的紧凑型多传感器设备问世,它配备了用于测量血氧张力的小型化克拉克电极以及用于测量二氧化碳张力、pH值和温度的两根光纤(Paratrend 7,生物医学传感器公司,英国海威科姆)。我们使用这种新型探头对颈静脉球进行连续血气监测,以替代常用的光纤分光光度法测量血红蛋白饱和度。
一名64岁患者因右侧颅内动脉瘤入院接受手术。手术期间,未出现伪迹或导管漂移迹象,测得颈静脉血氧分压(pjvO2)正常,为39±3毫米汞柱。在撤机期间,pjvO2出现两次下降(分别为22.5和18.7毫米汞柱),同时伴有二氧化碳张力下降和pH值升高。我们通过镇痛镇静、吸入氧分数为70%的控制通气以及将平均动脉血压升高至100毫米汞柱以上成功处理了这些情况。约24小时后得以拔管。此外,拔管后3小时,尽管患者有活动,但仍能顺利监测pjvO2值。
使用克拉克型探头极谱法测量pjvO2的技术似乎优于光纤颈静脉血氧测定法,因为测量误差的发生率明显更低,尤其是在重症监护病房,患者经常接受护理干预且容易苏醒。我们甚至在拔管后未观察到因患者活动导致的伪迹。新的多传感器系统的一个局限性可能是传感器尖端与插入导管末端之间有4厘米的距离,这使得为控制连续监测而抽取的用于体外血气分析的样本可比性较差。建议对探头的结构进行改进。