Padhye A A, Gutekunst R W, Smith D J, Punithalingam E
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, USA.
J Clin Microbiol. 1997 Aug;35(8):2136-41. doi: 10.1128/jcm.35.8.2136-2141.1997.
An immunocompetent 59-year-old man developed sinusitis over a 6- to 8-month period after cutting down a rotted maple tree (Acer sp.). A polypoid obstruction with a bloody drainage was evident in his right nasal cavity. A computed tomographic scan showed an opacification of the maxillary sinus. Surgery was performed to remove a fungus ball that had extended into the patient's medial sinus cavity. Sections of the sinonasal mucosa revealed marked acute and chronic sinusitis with inflammation, congestion, and hemorrhage. Sections from the pasty brown to black debrided material revealed a fungus ball consisting of an extensive network of brown-pigmented, septate, profusely branched hyphae. When grown on oat agar, the phaeoid fungus produced pycnidia and was identified as Pleurophomopsis lignicola. The genus Pleurophomopsis includes seven species, which are all known from plant material. This report documents for the first time a coelomycetous fungus, P. lignicola, causing sinusitis in an immunocompetent patient.
一名免疫功能正常的59岁男性在砍伐一棵腐烂的枫树（槭属）后的6至8个月内患上了鼻窦炎。其右侧鼻腔可见一个伴有血性分泌物的息肉样阻塞物。计算机断层扫描显示上颌窦混浊。进行了手术以切除延伸至患者鼻窦内侧腔的真菌球。鼻窦黏膜切片显示有明显的急慢性鼻窦炎，伴有炎症、充血和出血。从灰白色至黑色的清创材料切片中可见一个真菌球，由广泛的棕色色素、有隔膜、大量分支的菌丝网络组成。当在燕麦琼脂上培养时，该暗色真菌产生分生孢子器，被鉴定为木生侧茎点霉。侧茎点霉属包括七个物种，均从植物材料中发现。本报告首次记录了一种腔孢纲真菌——木生侧茎点霉，在一名免疫功能正常的患者中引起鼻窦炎。
