Cauchi M N, Goriup D, Horacek I
Aust N Z J Obstet Gynaecol. 1979 Feb;19(1):25-7. doi: 10.1111/j.1479-828x.1979.tb01346.x.
Beta 2 microglobulin (beta 2 m) levels were measured in amniotic fluids taken after the 32nd week of gestation. Beta 2 m levels fell continuously from 5.2 microgram/ml at the 32nd week to 3.08 microgram/ml after the 39th week of gestation. Abnormally high levels of beta 2 m were found in 12.6% of samples. There was a significant correlation between beta 2 m levels and lecithin/sphingomyelin ratios at 32 weeks of gestation and with creatinine levels at 37-38 weeks (P less than .05). Although elevated beta 2 m levels may be associated with maternal and/or fetal abnormalities, the precise relationship is not clearly established: in particular, our data do not suggest that estimation of beta 2 m levels could be of value in determining fetal maturity.
在妊娠32周后采集的羊水样本中测量β2微球蛋白（β2m）水平。β2m水平从妊娠32周时的5.2微克/毫升持续下降至妊娠39周后的3.08微克/毫升。在12.6%的样本中发现β2m水平异常升高。在妊娠32周时，β2m水平与卵磷脂/鞘磷脂比值以及在妊娠37 - 38周时与肌酐水平之间存在显著相关性（P < 0.05）。尽管β2m水平升高可能与母体和/或胎儿异常有关，但确切关系尚未明确确立：特别是，我们的数据并不表明β2m水平的测定在确定胎儿成熟度方面具有价值。
