Hintschich C R, Stefani F H
Augenklinik, Ludwig-Maximilians-Universität München.
Klin Monbl Augenheilkd. 1997 Apr;210(4):219-24. doi: 10.1055/s-2008-1035045.
Keratoacanthoma of the eyelid is a benign skin lesion. Because it regresses spontaneously observation without surgical intervention is the generally accepted method of management. This concept, which was developed in the sixties, is questioned on the basis of personal experience and a review of the literature. Recommendations for a rational management of the disease are suggested.
Two patients with clinically diagnosed eyelid keratoacanthomas are reported with their complicated disease course. A review of the dermatological and ophthalmic literature is presented.
For the correct diagnosis a sufficiently large and representative histological specimen is mandatory. The difficulty of differentiating between keratoacanthoma and squamous cell carcinoma is stressed. Surgery of advanced eyelid lesions is so much more destructive that early simple excision is advocated rather than a policy of initial observation.
眼睑角化棘皮瘤是一种良性皮肤病变。由于其可自发消退,因此一般公认的处理方法是观察而不进行手术干预。这一在60年代形成的观念,基于个人经验和文献回顾受到了质疑。本文提出了对该疾病合理处理的建议。
报告了2例临床诊断为眼睑角化棘皮瘤的患者及其复杂的病程。并对皮肤科和眼科文献进行了回顾。
为做出正确诊断,必须要有足够大且具有代表性的组织学标本。强调了鉴别角化棘皮瘤和鳞状细胞癌的困难。晚期眼睑病变的手术破坏性更大,因此主张早期进行简单切除,而非一开始就采取观察策略。