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[慢性非特异性肺部疾病患者的鲁米诺依赖性中性粒细胞化学发光]

[Luminol-dependent neutrophilic chemiluminescence in patients with chronic nonspecific lung diseases].

作者信息

Insanov A B, Alieva L S, Abdullaev F M, Umniashkin A A

机构信息

NII of Phthisiology and Pulmonology, Baku.

出版信息

Probl Tuberk. 1997(2):47-8.

PMID:9235592
Abstract

To assess the prognostic value of neutrophilic chemiluminescence, an examination was made of 68 patients with chronic bronchitis, 96 with bronchial asthma, and 34 apparently healthy individuals. Metabolic activity was determined by spontaneous and induced chemiluminescence in the whole blood and neutrophilic samples (the procedure being given). Patients with chronic bronchitis or bronchial asthma were found to have much higher metabolic activity in the neutrophils. The high sensitivity of chemiluminescence enables it to be used to determine the natural history of a disease and to check up the efficiency of treatment.

摘要

为评估中性粒细胞化学发光的预后价值,对68例慢性支气管炎患者、96例支气管哮喘患者及34名健康对照者进行了检测。通过全血和中性粒细胞样本的自发及诱导化学发光来测定代谢活性(具体步骤已给出)。发现慢性支气管炎或支气管哮喘患者的中性粒细胞代谢活性明显更高。化学发光的高灵敏度使其可用于确定疾病的自然病程及检查治疗效果。

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