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Pharmacokinetics of methyldopa in healthy man.

作者信息

Stenbaek O, Myhre E, Rugstad H E, Arnold E, Hansen T

出版信息

Eur J Clin Pharmacol. 1977 Oct 14;12(2):117-23. doi: 10.1007/BF00645132.

DOI:10.1007/BF00645132
PMID:923625
Abstract
摘要

相似文献

1
Pharmacokinetics of methyldopa in healthy man.
Eur J Clin Pharmacol. 1977 Oct 14;12(2):117-23. doi: 10.1007/BF00645132.
2
Pharmacokinetics of methyldopa in man.
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The pharmacokinetics of alpha-methyldopa in dogs.α-甲基多巴在犬体内的药代动力学。
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Conjugation of methyldopa in renal failure.
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Pharmacokinetics and presystemic gut metabolism of methyldopa in healthy human subjects.
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6
The renal excretion of methyldopa.
Scand J Clin Lab Invest. 1972 Apr;29(2):201-4. doi: 10.3109/00365517209081076.
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Pharmacokinetics of methyldopa. Plasma levels following single intravenous, oral and multiple oral dosage in normotensive and hypertensive subjects.
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8
Clinical pharmacokinetics of methyldopa.
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9
Metabolism of methyldopa in man after oral administration of the pivaloyloxyethyl ester.
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[Pharmacokinetics of alpha-methyldopa in kidney failure].
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引用本文的文献

1
Pharmacokinetics of the pivaloyloxyethyl (POE) ester of methyldopa, a new prodrug of methyldopa.甲基多巴的新前体药物——甲基多巴特戊酰氧乙酯的药代动力学
J Pharmacokinet Biopharm. 1982 Dec;10(6):587-600. doi: 10.1007/BF01062542.
2
Duration of effect of single daily dose methyldopa therapy.每日单次剂量甲基多巴治疗的作用持续时间。
Br J Clin Pharmacol. 1982 Jun;13(6):847-54. doi: 10.1111/j.1365-2125.1982.tb01877.x.
3
alpha-Methyldopa, alpha-methyldopamine an alpha-methylnoradrenaline: substrates for the thermolabile form of human platelet phenol sulphotransferase.

本文引用的文献

1
THE METABOLISM OF METHYLDOPA IN HYPERTENSIVE HUMAN SUBJECTS.甲基多巴在高血压患者中的代谢
J Pharmacol Exp Ther. 1964 Feb;143:205-14.
2
STUDIES ON THE METABOLISM AND MECHANISM OF ACTION OF METHYLDOPA.甲基多巴的代谢及其作用机制研究
Circulation. 1963 Oct;28:492-502. doi: 10.1161/01.cir.28.4.492.
3
Methyldopa in hypertension. Clinical and pharmacological studies.甲基多巴治疗高血压。临床与药理学研究。
α-甲基多巴、α-甲基多巴胺和α-甲基去甲肾上腺素：人血小板酚磺基转移酶热不稳定形式的底物。
Br J Clin Pharmacol. 1982 Aug;14(2):231-9. doi: 10.1111/j.1365-2125.1982.tb01967.x.
4
Clinical pharmacokinetics of methyldopa.
Clin Pharmacokinet. 1982 May-Jun;7(3):221-33. doi: 10.2165/00003088-198207030-00003.
5
The absorption and conjugation of methyldopa in patients with coeliac and Crohn's diseases during treatment.治疗期间乳糜泻和克罗恩病患者体内甲基多巴的吸收与结合情况
Br J Clin Pharmacol. 1983 Jul;16(1):77-83. doi: 10.1111/j.1365-2125.1983.tb02147.x.
6
The pharmacokinetics of alpha-methyldopa in dogs.α-甲基多巴在犬体内的药代动力学。
J Pharmacokinet Biopharm. 1985 Aug;13(4):405-23. doi: 10.1007/BF01061477.
7
Use of the peptide carrier system to improve the intestinal absorption of L-alpha-methyldopa: carrier kinetics, intestinal permeabilities, and in vitro hydrolysis of dipeptidyl derivatives of L-alpha-methyldopa.使用肽载体系统改善L-α-甲基多巴的肠道吸收：载体动力学、肠道通透性及L-α-甲基多巴二肽基衍生物的体外水解
Pharm Res. 1989 Jan;6(1):66-70. doi: 10.1023/a:1015855820488.
Lancet. 1962 Apr 14;1(7233):759-63. doi: 10.1016/s0140-6736(62)91781-6.
4
Combined clinical and metabolic study of the effects of alpha-methyldopa on hypertensive patients.
Circulation. 1966 Aug;34(2):308-21. doi: 10.1161/01.cir.34.2.308.
5
[Pharmacokinetics of alpha-methyldopa in kidney failure].
Klin Wochenschr. 1971 Dec 15;49(24):1329-34. doi: 10.1007/BF01495520.
6
Plasma turnover of methyldopa in advanced renal failure.
Acta Med Scand. 1972 Apr;191(4):343-7.
7
Hypotensive effect of methyldopa in renal failure associated with hypertension.
Acta Med Scand. 1972 Apr;191(4):333-7.
8
The renal excretion of methyldopa.
Scand J Clin Lab Invest. 1972 Apr;29(2):201-4. doi: 10.3109/00365517209081076.
9
Conjugation of methyldopa in renal failure.
Scand J Clin Lab Invest. 1972 Apr;29(2):195-9. doi: 10.3109/00365517209081075.
10
The metabolism of 14 C-labelled -methyldopa in normal and hypertensive human subjects.正常人和高血压患者体内14C标记的α-甲基多巴的代谢
Biochem J. 1972 Aug;129(1):1-10. doi: 10.1042/bj1290001.