Bernstein L J, Kauvar A N, Grossman M C, Geronemus R G
Laser and Skin Surgery Center of New York, New York 10016, USA.
Dermatol Surg. 1997 Jul;23(7):519-25. doi: 10.1111/j.1524-4725.1997.tb00677.x.
Carbon dioxide (CO2) laser resurfacing has become a very popular method of rhytide and scar removal in the recent past. Preliminary studies have been published describing the method, histology, and clinical results of CO2 laser resurfacing. However, none of these studies has dealt with long-term follow-up results.
To review all side effects resulting from CO2 laser resurfacing with regard to both short- and long-term effects.
Retrospective analysis of 104 patients who have undergone CO2 laser resurfacing for either facial rhytides and/or scarring with follow-up periods of 4-23 months (average, 8.2 months).
The incidence of side effects are generally very low for CO2 laser resurfacing, including scarring, postinflammatory hyperpigmentation, and infection. However, there is a significant and previously unreported risk of hypopigmentation in an area of the population who often seek improvement in the appearance.
CO2 laser resurfacing of facial rhytides and acne scars can be a very safe procedure by an experienced laser operator. However, careful patient selection, thorough patient instruction, and proper aesthetic analysis of treatment sites must be followed to insure the most favorable outcomes with CO2 laser resurfacing.
近年来，二氧化碳（CO2）激光换肤术已成为一种非常流行的去除皱纹和瘢痕的方法。已经发表了一些初步研究，描述了CO2激光换肤术的方法、组织学和临床结果。然而，这些研究均未涉及长期随访结果。
回顾CO2激光换肤术产生的所有短期和长期副作用。
对104例因面部皱纹和/或瘢痕接受CO2激光换肤术的患者进行回顾性分析，随访时间为4至23个月（平均8.2个月）。
CO2激光换肤术的副作用发生率通常很低，包括瘢痕形成、炎症后色素沉着和感染。然而，在经常寻求改善外貌的人群中，存在一种显著的、以前未报道过的色素减退风险。
由经验丰富的激光操作人员进行面部皱纹和痤疮瘢痕的CO2激光换肤术可以是一种非常安全的手术。然而，必须谨慎选择患者、对患者进行全面指导并对治疗部位进行适当的美学分析，以确保CO2激光换肤术获得最理想的效果。
