Vandeweyer E, Gebhart M
Department of Orthopedic Surgery, Jules Bordet Institute, Université Libre de Bruxelles, Belgium.
Eur J Surg Oncol. 1997 Jun;23(3):238-42. doi: 10.1016/s0748-7983(97)92460-4.
Between 1986 and 1993, 18 patients with complete or impending fractures of the humerus were treated using Hacketall rods in association with semi-liquid methylmetacrylate after excision of the metastatic lesion. Methylmetacrylate was always injected proximally and distally to the curetted bone through drill holes. Fourteen patients had a pathological fracture and four presented with an impending lesion. The mean age at time of surgery was 62 years (range: 42-83). The primary tumour was a breast carcinoma in 10 cases, bronchogenic squamous cell carcinoma in three cases and hypernephroma, multiple myeloma, malignant melanoma, rectal adenocarcinoma and unknown primary tumour in one case each. The left arm was involved in seven cases and the right in 11. All patients experienced immediate relief from the pre-operative pain, although three patients complained of a residual discomfort during motion. In these three cases the residual pain can easily be managed with use of oral non-morphinic drugs. The functional aspect was not evaluated in two patients who died in the early post-operative period as a result of their general condition. In 15 patients, the post-operative range of motion was at least 80% of a normal humerus mobility. One patient encountered motion limitation because of an important lymph oedema. There was no infection, one patient had a temporary radial palsy with a complete restoration after a period of 5 days. No migration of the material was observed during an average follow-up of 9 months (range: 1-24).
1986年至1993年间,18例肱骨完全骨折或即将骨折的患者在切除转移病灶后,使用哈克特棒并结合半液体甲基丙烯酸甲酯进行治疗。甲基丙烯酸甲酯总是通过钻孔在刮除骨的近端和远端注入。14例患者发生病理性骨折,4例表现为即将发生的病变。手术时的平均年龄为62岁(范围:42 - 83岁)。原发肿瘤为乳腺癌10例,支气管鳞状细胞癌3例,肾细胞癌、多发性骨髓瘤、恶性黑色素瘤、直肠腺癌各1例,原发肿瘤不明1例。左臂受累7例,右臂受累11例。所有患者术前疼痛均立即缓解,尽管3例患者在活动时仍有残余不适。在这3例中,残余疼痛可通过口服非吗啡类药物轻松控制。2例术后早期因全身状况死亡的患者未进行功能评估。15例患者术后活动范围至少为正常肱骨活动度的80%。1例患者因严重淋巴水肿出现活动受限。无感染发生,1例患者出现暂时性桡神经麻痹,5天后完全恢复。平均随访9个月(范围:1 - 24个月)期间未观察到材料移位。