Quiñones-Baldrich W J, Nene S M, Gelabert H A, Moore W S
Section of Vascular Surgery, University of California, Los Angeles (UCLA) Medical Center 90095-6904, USA.
Ann Vasc Surg. 1997 Jul;11(4):331-41. doi: 10.1007/s100169900057.
Twelve patients with rupture of the perivisceral abdominal aorta were admitted to the UCLA Medical Center between 1984 and 1996. Six patients had atherosclerotic thoracoabdominal aneurysms (TAA) which ruptured in the visceral segment of the aorta. The remaining 6 patients proved to have ruptured mycotic aneurysm (MA). Clinical presentation was different in the two groups. Whereas all 6 patients with TAA and < 24 hr history of abdominal, chest, or back pain, patients with MA had these symptoms for 2-5 weeks (mean 3.4 weeks). History of sepsis was present in 4/6 MA and in 0/6 TAA patients. No difference in risk factors for atherosclerosis were seen between these two groups. Clinical outcomes were also different. Operation consisted of in situ vascular grafting in all patients. Operative mortality for TAA was 33% (2/6), whereas all patients with MA survived repair with no operative mortality. Two patients had cardiac arrest prior to surgery. One of these had a TAA and died 5 days after surgery, whereas the other survived repair of an MA. Follow-up ranges from 1-84 months (mean 48 months). Four survivors in the TAA group are alive at 6, 8, 14, and 84 months, with the latter having a pseudoaneurysm of the visceral patch-graft anastomosis. All 6 patients with MA are alive at 1-73 months (mean 39 months) without evidence of graft sepsis or recurrent aneurysm. We conclude that rupture of the visceral portion of the aorta is often associated with a mycotic process, with important differences noted in clinical presentation when compared to atherosclerotic TAA. Surgical intervention is effective in both MA and TAA. Operative mortality, however, is significantly higher in patients with ruptured TAA. In situ prosthetic replacement for ruptured MA is associated with low mortality and excellent long-term results.
1984年至1996年间,12例腹主动脉周围破裂患者被收入加州大学洛杉矶分校医学中心。6例患者患有胸主动脉瘤(TAA)并在内脏段破裂。其余6例患者被证实患有感染性动脉瘤(MA)破裂。两组的临床表现不同。所有6例TAA患者均有腹部、胸部或背部疼痛且病史<24小时,而MA患者有这些症状2 - 5周(平均3.4周)。4/6的MA患者有败血症病史,而TAA患者中无此病史。两组间动脉粥样硬化的危险因素无差异。临床结果也不同。所有患者均采用原位血管移植术。TAA患者的手术死亡率为33%(2/6),而所有MA患者手术修复后均存活,无手术死亡。2例患者术前发生心脏骤停。其中1例为TAA患者,术后5天死亡,而另1例MA修复术后存活。随访时间为1 - 至84个月(平均48个月)。TAA组的4名幸存者分别在6、8、14和84个月时存活,后者在内脏补片移植吻合处有假性动脉瘤。所有6例MA患者在1 - 73个月(平均39个月)时存活,无移植感染或动脉瘤复发迹象。我们得出结论,主动脉内脏部分破裂常与感染过程相关,与动脉粥样硬化性TAA相比,临床表现有重要差异。手术干预对MA和TAA均有效。然而,TAA破裂患者的手术死亡率显著更高。MA破裂的原位人工血管置换术死亡率低且长期效果良好。