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真菌性主动脉瘤的外科治疗

Surgical Management of Mycotic Aortic Aneurysms.

作者信息

Aoki Chikashi, Fukuda Wakako, Kondo Norihiro, Minakawa Masahito, Taniguchi Satoshi, Daitoku Kazuyuki, Fukuda Ikuo

机构信息

Department of Thoracic and Cardiovascular Surgery, Hiro-saki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

出版信息

Ann Vasc Dis. 2017 Mar 24;10(1):29-35. doi: 10.3400/avd.oa.16-00117. Epub 2017 Mar 31.

Abstract

A mycotic aneurysm is an uncommon disease associated with a high mortality rate when managed surgically. This study reviewed our experiences in the surgical management of mycotic aortic aneurysms. In total, 26 patients who underwent surgery for a mycotic aneurysm were retrospectively reviewed. The mycotic aneurysms involved the thoracic aorta in 9 patients, the thoracoabdominal aorta in 4 patients, and the abdominal aorta in 13 patients. An overt aortic rupture in the mediastinum or retroperitoneal space was detected in 4 patients. Patients were classified into one of two groups, febrile or afebrile, and background characteristics, surgical intervention, and early and late mortalities were all compared. There were 19 patients who underwent open surgery, and 7 patients underwent endovascular repair. No significant differences in the clinical characteristics were found between the two groups; however, the incidence of postoperative complications was significantly higher in the febrile group than in the afebrile group (P=0.024). Overall mortality was 15.4% (4/26), and 30-day mortality was 7.7% (2/26). Although febrile patients had a higher incidence of postoperative complications, surgical mortality from a mycotic aneurysm was within an acceptable range. Each patient should be thoroughly evaluated and treated on a case-by-case basis, using conventional open repair, endovascular repair, or a combination of both approaches.

摘要

真菌性动脉瘤是一种罕见疾病,手术治疗时死亡率很高。本研究回顾了我们在真菌性主动脉瘤手术治疗方面的经验。总共对26例接受真菌性动脉瘤手术的患者进行了回顾性分析。真菌性动脉瘤累及胸主动脉9例,胸腹主动脉4例,腹主动脉13例。4例患者在纵隔或腹膜后间隙出现明显的主动脉破裂。患者被分为发热或不发热两组,并对其背景特征、手术干预以及早期和晚期死亡率进行了比较。19例患者接受了开放手术,7例患者接受了血管腔内修复。两组患者的临床特征无显著差异;然而,发热组术后并发症的发生率明显高于不发热组(P=0.024)。总体死亡率为15.4%(4/26),30天死亡率为7.7%(2/26)。尽管发热患者术后并发症的发生率较高,但真菌性动脉瘤的手术死亡率在可接受范围内。应根据具体情况对每位患者进行全面评估和治疗,采用传统的开放修复、血管腔内修复或两种方法联合使用。

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The changing management of primary mycotic aortic aneurysms.原发性真菌性主动脉瘤的治疗策略变迁。
J Vasc Surg. 2011 Aug;54(2):334-40. doi: 10.1016/j.jvs.2010.12.066. Epub 2011 Mar 31.
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