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在子宫内生活第6天接受300伦琴和200伦琴X射线照射的实验大鼠中出现遗传性阴道早熟开放。

Inheritable precocious opening of the vagina in laboratory rats exposed to 300 R and 200 R of X-rays on day 6 of their intrauterine life.

作者信息

Martinovitch P N, Zivković N, Pavić D

出版信息

Experientia. 1977 Nov 15;33(11):1438-9. doi: 10.1007/BF01918792.

DOI:10.1007/BF01918792
PMID:923702
Abstract

A highly significant inheritable advancement in opening of the vagina in laboratory rats has been induced by the X-ray application to pregnant females of different filial generations origination from the X-irradiated FO embryos. The reaction to X-rays has so far been followed through 9 filial generations.

摘要

对源自经X射线照射的F0代胚胎的不同子代的怀孕雌性大鼠应用X射线，已诱导出实验室大鼠阴道开口方面一项高度显著的可遗传进展。迄今为止，对X射线的反应已在9个连续子代中得到追踪。

相似文献

1
Inheritable precocious opening of the vagina in laboratory rats exposed to 300 R and 200 R of X-rays on day 6 of their intrauterine life.在子宫内生活第6天接受300伦琴和200伦琴X射线照射的实验大鼠中出现遗传性阴道早熟开放。
Experientia. 1977 Nov 15;33(11):1438-9. doi: 10.1007/BF01918792.
2
[Disorders of vaginal development in the progeny of white rats exposed to x-ray irradiation].
Arkh Anat Gistol Embriol. 1983 May;84(5):73-81.
3
[Experimental x-rays induced teratology and the general implications].
Arztl Forsch. 1972 Mar 10;26(3):87-95.
4
Teratogenic effect of fission neutron and tritium water on rat embryo.裂变中子和氚水对大鼠胚胎的致畸作用。
J UOEH. 1989 Mar 20;11 Suppl:416-31.
5
The effect of intrauterine position on the radiosensitivity of rat embryos.
Teratology. 1977 Oct;16(2):181-6. doi: 10.1002/tera.1420160212.
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Carcinogenic effect of radiation on the mouse embryo; physical aspects of radiation dosimetry.辐射对小鼠胚胎的致癌作用；辐射剂量学的物理方面。
Strahlentherapie. 1975 Dec;150(6):618-23.
7
The response of the 9 and one-half-day-old-rat embryo to variations in exposure rate of 150 R x-irradiation.
Radiat Res. 1971 Jan;45(1):127-36.
8
[Effects of fractionated radiotherapy on the fertility of mice irradiated in utero].
Strahlentherapie. 1972 Sep;144(3):324-37.
9
Effects of low-dose irradiation with x-rays and pi-mesons on embryos of two different mouse strains.低剂量X射线和π介子辐射对两种不同小鼠品系胚胎的影响。
Strahlentherapie. 1977 Oct;153(10):674-81.
10
[The pathogenesis of radiation injuries and the reparative processes in rat embryos after irradiation of the female with roentgen rays on the tenth day of pregnancy].[妊娠第10天对雌性大鼠进行X射线照射后大鼠胚胎辐射损伤的发病机制及修复过程]
Arkh Anat Gistol Embriol. 1960 Mar;38:72-9.

本文引用的文献

1
The onset of puberty after x-irradiation.X线照射后青春期的开始。
J Endocrinol. 1962 Mar;24:113-4. doi: 10.1677/joe.0.0240113.
2
The effect on the onset of puberty of whole body irradiation of infant female rats with and without hypothalamic lesions.
Experientia. 1968 Aug 15;24(8):839-40. doi: 10.1007/BF02144905.
3
Induction of hyperluteinization and precocious opening of the vagina in rats with a transverse cut in the hypothalamus made shortly after birth.出生后不久对大鼠下丘脑进行横切，可诱导其出现黄体化过度和阴道早熟开放。
Nature. 1968 Mar 2;217(5131):866-7. doi: 10.1038/217866a0.
4
The effects of x-irradiation, applied in infancy to the head region, on the reproductive system of female rats.
Experientia. 1970 Jan 15;26(1):95-6. doi: 10.1007/BF01900415.